Results 301 to 310 of about 91,428 (363)
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro+5 more
wiley +1 more source
Ubiquitin-conjugating enzyme E2 for regulating autophagy in diabetic cardiomyopathy: A mini-review. [PDF]
Zhou Y, Zheng Z, Wu S, Zhu J.
europepmc +1 more source
Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation [PDF]
Janine H. van Ree+3 more
openalex +1 more source
This study investigated how pomegranate juice affects inflammation in patients with inflammatory bowel disease who are currently in remission. After 12 weeks of drinking pomegranate juice, patients showed reduced markers of intestinal inflammation.
Ilaria Minato+25 more
wiley +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
[NIP7 upregulates the expression of ubiquitin-conjugating enzyme E2 C to promote tumor growth in anaplastic thyroid cancer]. [PDF]
Gong Y, Fang Z, Wang Y, Ge M, Pan Z.
europepmc +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella+6 more
wiley +1 more source
Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening. [PDF]
Loh YY+16 more
europepmc +1 more source
The ubiquitin conjugating enzyme UBE2L3 regulates TNFα-induced linear ubiquitination
Bishi Fu+4 more
semanticscholar +1 more source