Results 241 to 250 of about 80,046 (337)

Development of an efficient mice model of cancer‐associated cardiac cachexia

Animal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai   +9 more
wiley   +1 more source

Pellino ubiquitin ligases: double-edged swords in hematologic malignancies-from oncogenic stabilizers to therapeutic vulnerabilities. [PDF]

J Cancer Res Clin Oncol
Yang M, Li Y, Wang J.
europepmc   +1 more source

Pressure-Induced Differential Regulation of the Two Tryptophan Permeases Tat1 and Tat2 by Ubiquitin Ligase Rsp5 and Its Binding Proteins, Bul1 and Bul2

, 2003
Fumiyoshi Abe, Hidetoshi Iida
openalex   +1 more source

E3 Ubiquitin Ligases as Regulators of Membrane Protein Trafficking and Degradation [PDF]

, 2005
Alessandra d’Azzo, Antonella Bongiovanni, Tommaso Nastasi   +2 more
openalex   +1 more source

Advances in miRNA research: Unraveling the complexities of gene regulation

Animal Models and Experimental Medicine, EarlyView.
Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley   +1 more source

The Roles of E3 Ubiquitin Ligases in Cerebral Ischemia-Reperfusion Injury. [PDF]

Int J Mol Sci
Li M, Yu X, Liu Q, Fang Z, Wang H.
europepmc   +1 more source

Serum- and Glucocorticoid-Regulated Kinase 1 Regulates Ubiquitin Ligase Neural Precursor Cell-Expressed, Developmentally Down-Regulated Protein 4-2 by Inducing Interaction with 14-3-3 [PDF]

, 2005
Vivek Bhalla, Dorothée Daidié, Hongyan Li, Alan C. Pao, Lila P. LaGrange, Jian Wang, Alain Vandewalle, James D. Stockand, Olivier Staub, David Pearce   +9 more
openalex   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source

The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells [PDF]

, 2005
Jurgen A. Marteijn, Liesbeth van Emst, Claudia Erpelinck-Verschueren, Gorica Nikoloski, Aswin Menke, Théo de Witte, Bob Löwenberg, Joop H. Jansen, Bert A. van der Reijden   +8 more
openalex   +1 more source

Functional Analysis of the Pepper RING-Type E3 Ligase CaANKR1 Involved in Drought Stress Tolerance via Modulation of Abscisic Acid Signaling. [PDF]

Physiol Plant
Kim M, Lim CW, Kim DS, Lee SC.
europepmc   +1 more source