Results 41 to 50 of about 101,303 (167)

Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. [PDF]

, 2011
Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. Sebbene la disfunzione beta cellulare rivesta un ruolo di primaria importanza nel diabete di tipo 2, le informazioni ad
BUGLIANI, MARCO
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What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart [PDF]

, 2012
Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Benyhe, Sándor, Boyett, Marc, Dobrzynski, Halina, Dézsi, László, Erdélyi, Lajos, Papp, Gyula, Szalontai, Balázs, Szüts, Viktória, Varró, András, Vágvölgyi, Csaba, Zhang, Henggui, Ötvös, Ferenc   +11 more
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The comparative proteomics of ubiquitination in mouse [PDF]

, 2003
Ubiquitination is a common posttranslational modification in eukaryotic cells, influencing many fundamental cellular processes. Defects in ubiquitination and the processes it mediates are involved in many human disease states.
?, ?, Semple, Colin A M
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Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy [PDF]

, 2016
Prion diseases, such as bovine spongiform encephalopathies (BSE), are transmissible neurodegenerative disorders affecting humans and a wide variety of mammals.
A Aguzzi, A Balkema-Buschmann, A Buschmann, A Szutowicz, AC Straub, AG Biacabe, B Khaniya, C Casalone, C Loeuillet, Cristiano Corona, Cristina Casalone, DC Blomstrom, DK Nguyen, DS Tylee, DW Colby, Elena Vallino Costassa, Elena Xerxa, F Borovecki, F Shephard, G Lombardi, G Priemer, GA Wells, GD Penny, Gianluigi Zanusso, Giuseppe Legname, GK Smyth, GP Sawiris, H Filali, H Filali, H Filali, H Okada, Helena Krmac, HO Kim, J Hellemans, J Lyahyai, J Tan, J Vandesompele, J Ye, JA Richt, JG Jacobs, JM Torres, K Masujin, L Gautier, LM Almeida, M Barbisin, M Biagioli, M Seipelt, MA Reger, Maria Caramelli, Maria Novella Chieppa, Marion Simmons, Maura Barbisin, ME Bruce, MM Simmons, MP McKinley, MP Polak, NY Calingasan, Paolo Vatta, PJ Skinner, Q Kong, R Capobianco, R Johnson, R Sanges, R Tortosa, R Wang, R Wilson, RA Harris, RG Gardner, RG Wang, RG Will, S Booth, S Dudas, S Kabanova, S Lloyd, S Panelli, S Tester, S Zhang, SA Ness, SB Prusiner, ST Henderson, T Konold, TG Baron, U Basu, U Basu, V Beringue, W Huang da, W Huang da, Y Sun, Y Tang, Y Yamakawa   +89 more
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The CgHaa1-regulon mediates response and tolerance to acetic acid stress in the human pathogen Candida glabrata [PDF]

, 2016
To thrive in the acidic vaginal tract C. glabrata has to cope with high concentrations of acetic acid. The mechanisms underlying C. glabrata tolerance to acetic acid at low pH remain largely uncharacterized.
Aoyama, Toshihiro, Azeredo, Joana, Bernardo, Ruben T., Butler, Geraldine, Chibana, Hiroji, Cunha, Diana V., Mira, Nuno Pereira, Okamoto, Michiyo, Pereira, L. P., Salazar, Sara B., Schröder, Markus S., Silva, Sónia Carina, Sá-Correia, Isabel, Takahashi-Nakaguchi, Azusa, Wang, Can   +14 more
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Post-translational regulation of ubiquitin signaling

Journal of Cell Biology, 2019
Song and Luo review the roles of post-translational modifications in ubiquitin signaling.
Lei Song, Zhao-qing Luo
semanticscholar   +1 more source

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure [PDF]

, 2017
Background-Cardiac hypertrophy increases the risk of developing heart failure and cardiovascular death. The neutrophil inflammatory protein, lipocalin-2 (LCN2/NGAL), is elevated in certain forms of cardiac hypertrophy and acute heart failure.
Ala-Korpela, Mika, Bell, James R., Berzins, Stuart P., Booth, Scott A., Burrell, Louise M., Byars, Sean G., Charchar, Fadi J., Curl, Claire L., Delbridge, Lea M., Harrap, Stephen B., Havulinna, Aki, Inouye, Michael, Kahonen, Mika, Kangas, Antti J., Kelly, Jason, Kettunen, Johannes, Lehtimaki, Terho, Lewandowski, Paul A., Marques, Francine Z., McGlynn, Maree, Minoda, Yosuke, Patel, Sheila K., Perola, Markus, Prestes, Priscilla R., Raitakari, Olli, Raitoharju, Emma, Rana, Indrajeetsinh, Ritchie, Scott C., Ruohonen, Saku, Salomaa, Veikko, Soininen, Pasi, Srivastava, Piyush M., Wai, Bryan, Wlodek, Mary E., Wurtz, Peter   +34 more
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Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding

Science, 2019
Protein unfolding, one substrate at a time Ubiquitin marks proteins for degradation by the proteasome. However, many substrates cannot be directly degraded because they are well folded or are located in cell membranes or in multimeric complexes.
E. Twomey, Zhejian Ji, T. Wales, N. Bodnar, S. Ficarro, J. Marto, J. Engen, T. Rapoport   +7 more
semanticscholar   +1 more source

Proteomic Analysis of the Systemic Response to Radiographic Contrast Media [PDF]

, 2010
Introduction Radiographic contrast media (RCM) have numerous effects on the hemostatic system, inflammatory pathways, and vascular endothelium.
Armin Foghi, Charlotte Mobarak, Cheri Wells, Juan Martinez, Mark Ricciardi, Sarah Rohde, Warren K. Laskey   +6 more
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Identification of a putative protein-profile associating with tamoxifen therapy-resistance in breast cancer [PDF]

, 2009
Tamoxifen-resistance is a major cause of death in patients with recurrent breast cancer. Current clinical parameters can correctly predict therapy response in only half of the treated patients.
Bakker, M.A. (Michael) den, Foekens, J.A. (John), Jaitly, N. (Navdeep), Kang, H., Look, M.P. (Maxime), Martens, J.W.M. (John), Meijer van Gelder, M.E. (Marion), Paša-Tolić, L. (Ljiljana), Timmermans, A.M. (Mieke), Umar, A. (Arzu)   +9 more
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