Results 191 to 200 of about 282,971 (296)

Can neuromorphic computing help reduce AI's high energy cost? [PDF]

Proc Natl Acad Sci U S A
Ornes S.
europepmc   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

An Internet of Medical Things Cyber Security Assessment Model (IoMT-CySAM). [PDF]

Cureus
Jaidi F, Ksibi S, Bouhoula A.
europepmc   +1 more source

Dilute but Dense – Reversible Crosslinking Enables Water‐Rich (Bio)polymer Condensates

Advanced Science, EarlyView.
Reversible crosslinking between two types of (bio)polymers drives liquid–liquid phase separation even in good solvent. The arrangement of binding motifs controls condensate formation and density, and internal network structure. Simulations and theory reveal a closed‐loop coexistence phase diagram at very low monomer concentrations and re‐entrant ...
Xinxiang Chen, Jude Ann Vishnu, Pol Besenius, Julian König, Friederike Schmid   +4 more
wiley   +1 more source

The geo-politics of resilience: On the historical convergence between ecology, artificial intelligence, and corporate strategy. [PDF]

New Media Soc
Halpern O.
europepmc   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

A Physics-Aware Diffusion Framework for Robust ECG Synthesis Using Mesoscopic Lattice Boltzmann Constraints. [PDF]

Biology (Basel)
Qiu X, Cao H, Yang L, Wang H.
europepmc   +1 more source

Encoding Cumulation to Learn Perturbative Nonlinear Oscillatory Dynamics

Advanced Science, EarlyView.
Weak nonlinearities critically shape the long term behavior of oscillatory systems but are difficult to identify from data. A data‐driven framework is introduced to infer governing equations of weakly nonlinear oscillators from sparse and noisy observations.
Teng Ma, Ting‐Ting Gao, Wei Cui, Attilio Frangi, Gang Yan, Lin Zhao   +5 more
wiley   +1 more source

Disaggregated machine learning via in-physics computing at radio frequency. [PDF]

Sci Adv
Gao Z, Vadlamani SK, Sulimany K, Englund D, Chen T.   +4 more
europepmc   +1 more source

Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis

Advanced Science, EarlyView.
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen, Haidong Yu, Dongjiang Lin, Guojun Yang, Yuchen Xie, Yang Zhang, Jifeng Yuan   +6 more
wiley   +1 more source