Results 11 to 20 of about 1,159 (169)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate-binding pocket. [PDF]

open access: yesFEBS Lett
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Okada U, Murakami S.
europepmc   +2 more sources

A Monte Carlo simulation study comparing the up and down, biased-coin up and down and continual reassessment methods used to estimate an effective dose (ED95 or ED90) in anaesthesiology research

open access: yesBJA Open, 2023
Background: Dose-finding studies in anaesthesiology aim to target the effective dose (ED) of an anaesthetic agent in a specific population. The common dose-finding designs used are the up and down method (UDM), the biased-coin up and down (BCD), and the ...
Jean-François Fils   +3 more
doaj   +1 more source

Outcome of transforaminal epidural steroid injection for lumbar radiculopathy: initial three-year experience at Upendra Devkota Memorial-National Institute of Neurological and Allied Sciences, Nepal

open access: yesChinese Neurosurgical Journal, 2020
Background The prevalence of low back pain with radiculopathy in general population varies from 9.9% to 25%, which can be due to bony narrowing of the lateral recess or due to prolapsed intervertebral disc.
Pratyush Shrestha   +3 more
doaj   +1 more source

Association between stress hyperglycemia ratio and prognosis of patients hospitalized with COVID-19: A meta-analysis. [PDF]

open access: yesJ Diabetes Investig
This meta‐analysis found that a high stress hyperglycemia ratio (SHR) at admission is significantly associated with an increased risk of poor outcomes, including ICU admission, invasive mechanical ventilation, and in‐hospital mortality, in patients hospitalized with COVID‐19.
Chen L, Wang M, Chen J.
europepmc   +2 more sources

Green Synthesis of Ag/AgCl Nanoparticles From Argan Oil Waste: Characterization, Antibacterial, and Cytotoxicity Activities. [PDF]

open access: yesFood Sci Nutr
Ag/AgCl nanoparticles were biosynthesized using argan‐derived saponins and characterized by UV–Vis, FTIR, XRD, SEM/EDS, and TEM, confirming spherical structures averaging 12.3 ± 7.6 nm. The nanomaterials displayed a characteristic surface plasmon resonance at 400–450 nm and crystalline Ag/AgCl phases. Antibacterial performance against Gram‐positive and
El Kaourat A   +8 more
europepmc   +2 more sources

Utilization Driven Model for Server Consolidation in Cloud Data Centers

open access: yesIEEE Access, 2020
The application of cloud computing has diversified with the adoption of Internet of Things (IoTs) and edge computing. However, it has increased the uncertainty of workload demand; thus, the efficient utilization of cloud computing resources become more ...
Hammad Ur-Rehman Qaiser   +2 more
doaj   +1 more source

La montagne dans le sang

open access: yesBulletin de la Dialyse à Domicile, 2019
En France, près de 3 millions de personnes sont touchées par les maladies du rein. L’insuffisance rénale chronique touche environ 80 000 personnes. Sur ces 80 000 per¬sonnes touchées, 44 % d’entre elles bénéficient d’une greffe de rein, et 56 % sont ...
Fabrice Huré
doaj   +1 more source

Eleanor Roosevelt in Montreal

open access: yesJournal of Transnational American Studies, 2018
This article discusses First Lady Eleanor Roosevelt’s international travels during the Second World War. Mrs. Roosevelt achieved her greatest renown in the postwar period as a champion of international human rights, notably in her role as chair of the ...
Greg Robinson
doaj   +1 more source

On Dominant Oscillation Frequency of a Simplified Fluidic Oscillator

open access: yesJournal of Fluid Science and Technology, 2011
In the present study, we investigate a self-excited oscillatory phenomenon of a two-dimensional confined jet with a rectangular-cross-section cylinder as a downstream target.
Katsuya HIRATA   +5 more
doaj   +1 more source

Thermal-hydraulic performance prediction of two new heat exchangers using RBF based on different DOE

open access: yesOpen Physics, 2021
Thermal performance prediction with high precision and low cost is always the need for designers of heat exchangers. Three typical design of experiments (DOE) known as Taguchi design method (TDM), Uniform design method (UDM), and Response surface method (
Yu Chulin   +4 more
doaj   +1 more source

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