Results 41 to 50 of about 201,834 (269)
Advanced Science, EarlyView.High‐throughput screening led to the identification of 67 Z‐scheme heterojunctions (comprising 2D magnetic transition metal halides and non‐magnetic transition metal chalcogenides). For CrI3/MoTe2 and CrI3/WTe2, electronic structure analysis demonstrated that synergistic crystallographic point group and built‐in electric field effects generate a ...
Hongyang Ren +8 more
wiley +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Educação em Análise, 2019 Neste artigo debate-se a questão da educação literária e apresenta-se a implementação de uma proposta didática, para a exploração na sala de aula, de um livro de literatura para a infância, num entendimento de que a educação literária pressupõe a ...
Cláudia Pereira, Angela Balça
doaj +1 more source
Charge‐Transfer‐Mediated Boron Magneto‐Ionics: Towards Voltage‐Driven Multi‐Ion Transport
Advanced Science, EarlyView.This study demonstrates voltage‐driven multi‐ion transport in FeBO systems, revealing simultaneous motion of B, Fe, and O ions enabled by charge‐transfer effects. By tuning oxidation states through oxygen incorporation, we achieve a transition from electrostatic‐like to electrochemical magneto‐ionic behavior. The findings establish boron magneto‐ionics,
Zheng Ma +15 more
wiley +1 more source
Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Angewandte Chemie, EarlyView.Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
Advanced Science, EarlyView.A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati +10 more
wiley +1 more source
Del usar y tirar al reparar y conservar La Directiva (UE) 2024/1799 de 13 de junio de 2024 por la que se establecen normas comunes para promover la reparación de bienes y se modifican el Reglamento (UE) 2017/2394 y las Directivas (UE) 2019/771 y (UE) 2020/1828 [PDF]
La Unión Europea, paralelamente a la protección del mercado digital, ha abierto una nueva línea de protección del consumidor desde la perspectiva de la sostenibilidad.
Torrelles Torrea, Esther
core +5 more sources
Tunable Oxygen Connectivity in Carbaporphyrinoid Polymers on Metal Surfaces
Angewandte Chemie, EarlyView.Hydroxyl‐functionalized dicarbaporphyrinoid polymers synthesized on Au(111) enable tunable oxygen‐mediated connectivity under UHV conditions. Thermal activation yields one‐dimensional hydroxyl‐terminated polymers that can selectively evolve into either covalently‐linked dibenzo‐p‐dioxane architectures through intermolecular C–O–C coupling or two‐fold ...
Alberto Martínez‐Bajo +14 more
wiley +2 more sources
El Reglamento (UE) 650/2012: su impacto en las sucesiones transfronterizas
, 2020 Ressenya de: Dir.: M. E. Ginebra Molins y J. Tarabal Bosch.
Garriga Suau, Georgina
core +4 more sources
La Unión Europea como paradigma civil y político para el siglo xxi
Bajo Palabra, 2019 La UE constituye una novedad institucional y cívico política que plantea interrogantes a la teoría política. Por ello, resulta relevante tenerla en cuenta para pensar la ciudadanía y la comunidad política del siglo XXI, en un mundo globalizado y ...
Marta Postigo Asenjo
doaj +1 more source