Results 211 to 220 of about 49,542 (253)

Determination of carbapenems in water samples by UHPLC–MS/MS

Journal of Separation Science, 2020
AbstractA rapid and reliable method for the detection of five carbapenems (biapenem, imipenem, doripenem, meropenem, and faropenem) in water was developed and validated. After acidification of water samples with acetic acid, carbapenems were isolated using a Bond Elut PPL cartridge.
Chengfei Wang, Xiaowei Li, Ziquan Lv, Yingyu Wang, Yuebin Ke, Xi Xia   +5 more
openaire   +2 more sources

Quantitative Analysis of Bile Acid with UHPLC-MS/MS

2020
Bile acids are important end products of cholesterol metabolism, having been shown to serve as signaling molecules and intermediates between the host and the gut microbiota. Here we describe a robust and accurate method using ultrahigh-pressure liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) for the quantification of bile ...
Yuan, Tian, Jingwei, Cai, Erik L, Allman, Philip B, Smith, Andrew D, Patterson   +4 more
openaire   +2 more sources

Profiling of illicit fentanyl using UHPLC–MS/MS

Forensic Science International, 2012
Methodology is presented for the profiling of fentanyl in seized drugs using ultra high performance liquid chromatography in combination with tandem mass spectrometry (UHPLC-MS/MS). Target analysis was performed for 40 fentanyl processing impurities, several of which are markers for a specific synthetic route (Siegfried or Janssen).
Ira S, Lurie, Arthur L, Berrier, John F, Casale, Reiko, Iio, Joseph S, Bozenko   +4 more
openaire   +2 more sources

Study of Sangiovese Wines Pigment Profile by UHPLC-MS/MS

Journal of Agricultural and Food Chemistry, 2012
The metabolic pigment composition of Sangiovese wines produced from grapes harvested at 20 different vineyards in Montalcino over three consecutive years (2008-2010) on a semi-industrial scale and of 55 commercial Brunello di Montalcino wines (2004-2007) was studied, using a targeted method capable of analyzing 90 pigments in an 11 min UHPLC-MS/MS ...
Arapitsas, Panagiotis, Perenzoni, Daniele, Nicolini, Giorgio, Mattivi, Fulvio   +3 more
openaire   +3 more sources

Determination of higenamine in dietary supplements by UHPLC/MS/MS method

Journal of Pharmaceutical and Biomedical Analysis, 2017
From 1st January 2017 higenamine was added on the WADA (World Anti-doping Agency) Prohibited list under S3 group beta-2 agonists as at all times banned substance for the athletes. The main origine of higenamine (or norcoclaurine) are different plants including Nandina domestica, Aconitum carmichaelii, Asarum heterotropioides, Galium divaricatum, Annona
Stajić, Ana, Anđelković, Marija, Dikić, Nenad, Rasić, J., Vukašinović-Vesić, Milica, Ivanović, D., Jančić-Stojanović, Biljana   +6 more
openaire   +4 more sources

Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS

Analytical and Bioanalytical Chemistry, 2012
Monepantel (MOP) belongs to a new class of anthelmintic drugs known as aminoacetonitrile derivatives. It was approved for use in veterinary practice in Czech Republic in 2011. So far, biotransformation and transport of MOP in target animals have been studied insufficiently, although the study of metabolic pathways of anthelmintics is very important for
Lucie, Stuchlíková, Robert, Jirásko, Ivan, Vokřál, Jiří, Lamka, Marcel, Spulák, Michal, Holčapek, Barbora, Szotáková, Hana, Bártíková, Milan, Pour, Lenka, Skálová   +9 more
openaire   +2 more sources

Determination and pharmacokinetic study of skimmin by UHPLC-MS/MS in rat plasma

Journal of Pharmaceutical and Biomedical Analysis, 2020
Skimmin, a major active ingredient derived from Hydrangea paniculata, has been considered to possess various pharmacological activities, including renoprotective activity, anti-inflammatory, anti-cancer, and antiamoebic properties. However, no investigation has reported the quantification and pharmacokinetics of skimmin in biomatrices.
Yan, Lou, Hongyu, Wu, Jinqi, Zheng, Xiaoying, He, Zhe, Wu, Xiaoyang, Lu, Yunqing, Qiu   +6 more
openaire   +2 more sources

Pharmacokinetic and bioavailability study of kurarinone in dog plasma by UHPLC–MS/MS

Biomedical Chromatography, 2020
AbstractKurarinone, a natural prenylated flavonone isolated from Sophora flavescens, has been exhibited various activities. This study aimed to establish a simple and sensitive ultra‐high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method for determining kurarinone in dog plasma.
Yiqian Huang, Huashan Lin, Yaping Chen, Xiaosong Huang   +3 more
openaire   +2 more sources

Micro-UHPLC-MS/MS method for analysis of oxylipins in plasma and platelets

Journal of Pharmaceutical and Biomedical Analysis, 2020
Oxylipins play an important role in cell signaling and they act as auto- and paracrine factors. There are numerous reports on the analysis of oxylipins in biofluids, especially in plasma. Only a limited number of studies addressed the analysis of oxylipins in platelets using modern, sensitive LCMS methods, even though these compounds have a huge impact
Malgorzata Cebo, Xiaoqing Fu, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer   +4 more
openaire   +2 more sources

Polyether ionophores residues in Minas Frescal cheese by UHPLC-MS/MS

Food Additives & Contaminants: Part B, 2020
An analytical method was developed and validated for the determination of three polyether ionophores (monensin, lasalocid, and salinomycin) in 60 samples of Brazilian Minas Frescal cheese by UHPLC-MS/MS. Linearity ranged from 1 to 8 μg kg-1 for monensin and salinomycin, and from 0.50 to 4 μg kg-1 for lasalocid. Limits of detection and quantitation were
Felipe R N, Silva, Andrea R, Bortolotte, Patricia A de C, Braga, Felix G R, Reyes, Adriana P, Arisseto-Bragotto   +4 more
openaire   +2 more sources