Results 131 to 140 of about 803,265 (414)

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui, Meng Yang, Chengli Yu, Haidong Zhang, Yuan Gong, Yang Hu, Yue Wang, Qingxin Yuan, An Pan, Jiepin Li, Yaowen Hu, Zecheng Jin, Xuemei Peng, Anyuan Wu, Junwei Wang, Qian Wang, Yinan Zhang, Lihong Hu   +17 more
wiley   +1 more source

Mycobacterium ulcerans infection: control, diagnosis, and treatment. [PDF]

, 2006
The skin disease Buruli ulcer, caused by Mycobacterium ulcerans, is the third most common mycobacterial disease after tuberculosis and leprosy and mainly affects remote rural African communities. Although the disease is known to be linked to contaminated
Adjei, Amofah, Amofah, Andries, Aujoulat, Bentoucha, Darie, Debacker, Debacker, Debacker, Dega, Dega, Dhople, Dhople, Dhople, Drummond, Eddyani, Eric Comte, Espey, Etuaful, Evans, Evans, Fabienne Nackers, Fehr, Françoise Portaels, Guédénon, Hospers, Huygen, Johnson, Johnson, Johnson, Kanga, Kanga, Kanga, Klutse, Marsollier, Marsollier, Marsollier, Marsollier, Marsollier, Marston, Meyers, Mve-Obiang, Nakanaga, Noeske, Okenu, Phillips, Phillips, Portaels, Pszolla, Raghunathan, Revill, Rhodes, Scott, Siegmund, Smith, Stienstra, Stienstra, Stragier, Tanghe, Thangaraj, van der Werf, van der Werf, Veitch, Vinciane Sizaire   +64 more
core   +2 more sources

DYSPEPSIA OR ULCER? [PDF]

The Lancet, 1915
n ...
openaire   +2 more sources

History of Helicobacter pylori, duodenal ulcer, gastric ulcer and gastric cancer.

World Journal of Gastroenterology, 2014
Helicobacter pylori (H. pylori) infection underlies gastric ulcer disease, gastric cancer and duodenal ulcer disease. The disease expression reflects the pattern and extent of gastritis/gastric atrophy (i.e., duodenal ulcer with non-atrophic and gastric ...
D. Graham
semanticscholar   +1 more source

Accurate Delivery of Mesenchymal Stem Cell Spheroids With Platelet‐Rich Fibrin Shield: Enhancing Survival and Repair Functions of Sp‐MSCs in Diabetic Wound Healing

Advanced Science, EarlyView.
Autologous plasma‐derived platelet‐rich fibrin (PRF) is prepared as a protective shield for mesenchymal stem cell spheroids (Sp‐MSCs). PRF forms a fibrin shield to protect Sp‐MSCs from the oxidative stress environment. The nutrients in PRF, particularly the α‐granules, can enhance the repair function of Sp‐MSCs.
Jinglve Zhang, Wenqing Xu, Yutian Xiao, Dingheng Su, Yusheng He, Huohong Yang, Yixin Xie, Xiaofang Wang, Ren‐He Xu, Shaorong Lei, Dingyu Wu   +10 more
wiley   +1 more source

Increased expression of two alternative spliced variants of CD1d molecule in human gastric cancer [PDF]

, 2015
Background: CD1d presents glycolipid antigens to invariant natural killer T (iNKT) cells. The role of CD1d in the development of peptic ulcer and gastric cancer has not been revealed, yet.
Ajami, A., Alizadeh-Navaei, R., Farazmandfar, T., Hafezi, N., Hosseini, V., Tehrani, M.   +5 more
core  

PEPTIC ULCER

Annals of Surgery, 1922
n ...
openaire   +4 more sources

Risk Factors for Plantar Foot Ulcer Recurrence in Neuropathic Diabetic Patients

Diabetes Care, 2014
OBJECTIVE Recurrence of plantar foot ulcers is a common and major problem in diabetes but not well understood. Foot biomechanics and patient behavior may be important. The aim was to identify risk factors for ulcer recurrence and to establish targets for
R. Waaijman, M. de Haart, M. Arts, D. Wever, Anke Verlouw, F. Nollet, S. Bus   +6 more
semanticscholar   +1 more source

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

Advanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu, Amarnath Marudamuthu, Khadija Kakar, Hamida Hamida, Shruthi Thada, Rohan Gupta, Kiesha Wilson, Taylor Carter, Yin Zhong, Archana Saxena, Xiaoming Yang, Narendra Singh, Philip Brandon Busbee, Jie Li, Monica Garcia‐Buitrago, Prakash Nagarkatti, Mitzi Nagarkatti   +16 more
wiley   +1 more source

A Refined Deep Learning Architecture for Diabetic Foot Ulcers Detection [PDF]

arXiv, 2020
Diabetic Foot Ulcers (DFU) that affect the lower extremities are a major complication of diabetes. Each year, more than 1 million diabetic patients undergo amputation due to failure to recognize DFU and get the proper treatment from clinicians. There is an urgent need to use a CAD system for the detection of DFU.
arxiv