Results 131 to 140 of about 288,502 (268)

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Effectiveness of Total Contact Casting in the Treatment of Neuropathic Plantar Ulcers: An Observational Study. [PDF]

Cureus
Kataruka M, Sannyashi P, Bhattacharjee S, Sajeev A.   +3 more
europepmc   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

Cytomegalovirus-induced cutaneous ulcers: A case series

JAAD Case Reports
Shruti Agrawal, MD, Seneca D. Hutson, MD, Emma F. Johnson, MD, Afsaneh Alavi, MD   +3 more
doaj   +1 more source

Case Report of <i>Rhodococcus erythropolis</i> Contamination in Buruli Ulcer Lesions: Effects on <i>Mycobacterium ulcerans</i> Diagnosis. [PDF]

Case Rep Infect Dis
Zeukeng F, Amedior JS, Ndzodo EF, Kakou-Ngazoa SE, Ghogomu SM, Coulibaly DN, Mbacham WF, Bigoga JD, Ablordey A.   +8 more
europepmc   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Punched-out gluteal and perianal ulcerations

JAAD Case Reports
Sarah Williamson, MD, Julie Iacullo, MD, Harry Winfield, MD   +2 more
doaj   +1 more source

A Conceptual Bi-Dimensional Risk Assessment Framework in Bleeding Peptic Ulcers. [PDF]

J Clin Med
Langellotti L, Tirelli F, Mangiola F, Pontecorvi V, Landi R, Rodolfino E, Iezzi R, Pelanda H, Rosa F, Alfieri S.   +9 more
europepmc   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Profiling Mycobacterium ulcerans with hsp65

Emerging Infectious Diseases, 2005
Sylvia Cardoso Leão, Jorge Luiz Mello Sampaio, Anandi Martin, Juan Carlos Palomino, Françoise Portaels   +4 more
doaj   +1 more source