Effectiveness of an Affordable Toa Uzito Offloading Device for Healing Plantar Diabetic Foot Ulcer: A Matched Case-Control Clinical Study. [PDF]
Abbas ZG, Naemi R.
europepmc +1 more source
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan +13 more
wiley +1 more source
Punched-out gluteal and perianal ulcerations
Sarah Williamson, MD +2 more
doaj +1 more source
Computational, In Vitro, and In Vivo Evaluation of Benzimidazole-Pyrazole Hybrid Scaffolds as Multi-Target Anti-Ulcer Agents. [PDF]
Kharl HAA +8 more
europepmc +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Profiling Mycobacterium ulcerans with hsp65
Sylvia Cardoso Leão +4 more
doaj +1 more source
Kissing Rectal Ulcers With Associated Occult Rectal Mucosal Prolapse: A Distinct Endoscopic Presentation of Solitary Rectal Ulcer Syndrome in an HIV Positive Patient With Comprehensive Infectious Exclusion. [PDF]
Ganju N +6 more
europepmc +1 more source
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Summary of the best evidence for stress ulcer prophylaxis in critically ill patients. [PDF]
Wang J +8 more
europepmc +1 more source

