Results 221 to 230 of about 595,924 (360)

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

Advanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou, Meijing Wang, Shunji Liu, Limei Gu, Shijia Liu, Qianming Du, Tianyi Zhang, Yinuo Ma, Lixin Zhao, Jiaming Wang, Qiang Xu, Tingsheng Ling, Haibo Cheng, Hongqi Chen, Yang Sun   +14 more
wiley   +1 more source

Factors contributing to bleeding and perforated peptic ulcers in Syria: findings from a multicenter cohort study. [PDF]

Int J Emerg Med
Ataya J, Hasan YH, Daboul R, Hanifa H, Bannoud N, Alnabi NAA, Watfa M, Jomaa M, Hamed H, Alhaj A.   +9 more
europepmc   +1 more source

Senescence‐Inducing Therapy Sequential NIR‐II Mild Photothermal/Senolytic Therapy of Triple Negative Breast Cancer

Advanced Science, EarlyView.
Targeting triple‐negative breast cancer remains challenging due to limited therapies and drug resistance. A sequential theranostic strategy combining palbociclib‐induced senescence (enhancing heat sensitivity via HSP70 downregulation) with an NIR‐II nanoplatform (IQ NPs) for mild photothermal therapy (PTT) and quercetin‐mediated senolysis is developed.
Liya Yu, Yehui Kang, Mengdie Yu, Yuejia Ding, Yang Chen, Qingyuan Wu, Yu Cai, Huiyu Liu, Zhenye Lv   +8 more
wiley   +1 more source

Curative Resection Following Conservative Treatment for Perforated Early Gastric Cancer: A Case Report. [PDF]

Clin Case Rep
Yoshizawa J, Sugiyama S, Kubota K, Nakayama A.   +3 more
europepmc   +1 more source

“Mooren's” Ulcer Associated with Ulceration of the Sclerotic [PDF]

Proceedings of the Royal Society of Medicine, 1913
openaire   +3 more sources

Dnmt1 Alleviates S1PR1‐Mediated Pyroptosis after Spinal Cord Injury through Regulating Pon3 Expression

Advanced Science, EarlyView.
This study systematically explores the action mechanism of Pon3 and its regulatory targets in spinal cord injury (SCI). It demonstrates that Dnmt1 regulates Pon3 expression by modulating methylation levels, thereby inhibiting S1PR1‐mediated pyroptosis and improving SCI prognosis.
Birong Peng, Haolong Lin, Mi Zhang, Wenhao Kuang, Jiaqi Zhang, Shuai Wang, Yuanfang Sun, Wenning Xu, Lixin Zhu   +8 more
wiley   +1 more source

Successful healing of a chronic ulcer in livedoid vasculopathy using PuraPly: A case report

JAAD Case Reports
Sofia Angel, BS, Brenley Deters, PA-C, Jaeyoung Yoon, MD, PhD, Lindsey Graviett, MD   +3 more
doaj   +1 more source

A Borate-Based Bioactive Glass Advances Wound Healing in Non-Healing Wagner Grade 1 Diabetic Foot Ulcers: A Randomised Controlled Clinical Trial. [PDF]

Int Wound J
Armstrong DG, Orgill DP, Galiano RD, Lantis J, Glat PM, Gitterle M, Carter MJ, Young N, Zelen CM.   +8 more
europepmc   +1 more source

CHRONIC DUODENAL ULCER* PROCEDURES AS DETERMINED BY THE OPERATIVE PATHOLOGY

, 1940
J. William Hinton, ROLAND L. MAIER
openalex   +2 more sources

Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review

Advanced Science, EarlyView.
This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren, Fuyao Liu, Yanan Zhong, Shengbo Ge, Zhipeng Shi, Siling Lin, Hongli Song, Yingying Zhang, Wei Fan   +8 more
wiley   +1 more source