Results 261 to 270 of about 803,265 (414)

Comparative analysis of short‐term and long‐term LL‐37‐induced rosacea‐like mouse models: Histopathological features and inflammatory immune responses

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The aim of this study was to improve the long‐term LL‐37 mouse model and compare the disease manifestations and pathophysiology of short‐term and long‐term LL‐37‐induced rosacea‐like models. The results show that the long‐term LL‐37 induced mouse model provides a practical animal model for further study of the pathological mechanism of severe rosacea ...
Yiling Wu   +10 more
wiley   +1 more source

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera   +11 more
wiley   +1 more source

Rétrograde venous perfusion (RVP) for intraçtable venous leg ulcers: a retrospective analysis. [PDF]

open access: yesEur J Med Res
Sharabi A   +6 more
europepmc   +1 more source

Hydrophilic Particles Exit While Hydrophobic Particles Persist Following In Vivo Biodegradation of Nanoparticle‐Laden Polymeric Devices

open access: yesAdvanced NanoBiomed Research, EarlyView.
Functionalizing biomedical implants with nanoparticle contrast agents introduces imaging capabilities to devices, improving patient care by avoiding inherent complications. However, nanoparticle surface chemistry optimized for device manufacturing may not lead to efficient nanoparticle clearance from tissues.
Kendell M. Pawelec   +4 more
wiley   +1 more source

Machine learning‐augmented molecular dynamics simulations (MD) reveal insights into the disconnect between affinity and activation of ZTP riboswitch ligands

open access: yesAngewandte Chemie International Edition, Accepted Article.
The challenge of targeting RNA with small molecules necessitates a better understanding of RNA‐ligand interaction mechanisms. However, the dynamic nature of nucleic acids, their ligand‐induced stabilization, and how conformational changes influence gene expression pose significant difficulties for experimental investigation.
Christopher Fullenkamp   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy