Results 81 to 90 of about 6,878 (214)

Adalimumab for refractory peripheral ulcerative keratitis [PDF]

Journal of Ophthalmic Inflammation and Infection, 2012
Peripheral ulcerative keratitis (PUK) is an immune-mediated disorder characterized by patchy, peripheral stromal thinning and infiltrates which tend to coalesce and extend to the limbus and often the sclera (unlike Mooren's ulcer) even in the presence of an intact overlying epithelium [1].
Cordero-Coma, Miguel, Méndez, Raquel Salazar, Blanco, Álvaro Casado, Corral, Ana López, Calleja-Antolín, Sara, Morales, José M. Ruiz   +5 more
openaire   +2 more sources

What We Can Do in Infectious Keratitis, Except for Conventional Antimicrobial‐Based Therapies: Major Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Infectious keratitis (IK) is classified as a critical ophthalmic emergency, with the potential to result in vision‐impairing complications. The treatment approach involves the use of pharmacological antimicrobial agents in combination with surgical interventions.
Kasra Cheraqpour
wiley   +1 more source

Bilateral Corneal Ulceration Caused by Vitamin A Deficiency in Eosinophilic Gastroenteropathy

Case Reports in Ophthalmology, 2011
Purpose: Vitamin A deficiency is a very rare condition in the developed world and can lead to a variety of ocular changes from xerosis and xerophthalmia to corneal ulcer and perforation. The treatment of this devastating disease is simple and inexpensive.
Alex P. Lange, Greg Moloney, Claire A. Sheldon, Sachiko Sasaki, Simon P. Holland   +4 more
doaj   +1 more source

The Contact Lens Impact on Quality of Life (CLIQ) questionnaire: development and validation [PDF]

, 2009
NoPURPOSE. To develop and validate a questionnaire for the measurement of the impact of contact lenses on quality of life (QoL): The Contact Lens Impact on Quality of Life (CLIQ) Questionnaire. METHODS. The questionnaire was developed and validated using
Elliott, David B., Garamendi, Estibaliz, Pesudovs, Konrad   +2 more
core   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Infliximab for Peripheral Ulcerative Keratitis Treatment

Medicine, 2014
Biologic agents such as anti-TNFα have been employed in treatment paradigms for ocular inflammation. Peripheral corneal ulceration (PUK) is a devastating disorder consisting of a crescent-shaped area of destructive inflammation at the margin of the corneal stroma.
Huerva, V., Ascaso, F. J., Grzybowski, A.   +2 more
openaire   +4 more sources

Supercationic Poly(Hexamethylene Biguanide)‐Derived Carbon Dots for Combating Multidrug‐Resistant Bacterial Keratitis

Small Structures, Volume 7, Issue 3, March 2026.
This research introduces poly(hexamethylene biguanide)‐derived carbon dots (P‐CDs) as a novel antibacterial agent for combating multidrug‐resistant bacterial keratitis. P‐CDs exhibit potent activity against resistant pathogens, including MRSA and MRPA. In vivo results confirm their superior therapeutic efficacy over standard antibiotics, alongside the ...
Wenjie Fan, Tianji Feng, Hongxian Pan, Yin Zhang, Zhebin Chen, Qiao Jin, Haijie Han, Jian Ji, Ke Yao   +8 more
wiley   +1 more source

How Could Contact Lens Wearers Be at Risk of Acanthamoeba Infection? A Review

Journal of Optometry, 2009
Contact lens wear is highly influential on the incidence of ulcerative keratitis worldwide, particularly in developed countries. The association between Acanthamoeba keratitis and contact lens wear is firmly established; it may account for up to 95% of ...
Youhanna W. Ibrahim, David L. Boase, Ian A. Cree   +2 more
doaj   +1 more source

Adhesion of Pseudomonas aeruginosa and Staphylococcus epidermidis to silicone-hydrogel contact lenses [PDF]

, 2005
Purpose. The purpose of this study is to compare the adhesion capabilities of the most important etiologic agents of microbial ocular infection to the recently available silicone– hydrogel lenses with those to a conventional hydrogel lens. Methods.
Azeredo, Joana, Henriques, Mariana, Lira, Madalena, Oliveira, Rosário, Real Oliveira, M. Elisabete C.D., Sousa, Cláudia Miriam Pereira   +5 more
core   +1 more source

Angiopoietin‐1, Angiopoietin‐2 and Vascular Endothelial Growth Factor Levels in Canine Leishmaniosis

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Ang‐1, Ang‐2 and VEGF levels significantly varied in different stages of canine leishmaniosis. ABSTRACT Background Canine leishmaniosis (CanL) is a zoonotic vector–borne disease and is primarily associated with systemic inflammation, endothelial dysfunction and immune dysregulation.
Gamze Gultekin, Erdogan Malatyali, Evren Tileklioglu, Hatice Ertabaklar, Songul Erdogan, Gamze Sevri Ekren Asici, Asude Gulce Oryasin, Serdar Pasa, Kerem Ural, Hasan Erdogan, Mehmet Gultekin   +10 more
wiley   +1 more source