Therapy with Ulipristal Acetate in a Hypertensive Patient [PDF]
Case Reports in Medicine, 2018 Ulipristal acetate (UPA) is a medical therapy for patients with symptomatic uterine fibroids. The drug has shown efficacy in the control of heavy menstrual bleeding and, as a consequence, in anaemia improvement.
A. Alcalde Dominguez +3 more
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Ulipristal Acetate in Adenomyosis. [PDF]
Gynecol Minim Invasive Ther, 2022 Adenomyosis is defined as the invasion of the basal endometrium (stroma and glands) into the underlying myometrium. It may lead to abnormal uterine bleeding (AUB), pelvic pain, and infertility. The definitive treatment is hysterectomy. Some conservative measures have been used in patients willing to procreate.
Gonçalves-Henriques M +6 more
europepmc +3 more sources
Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON): a randomised controlled phase III trialResearch in context [PDF]
EClinicalMedicine, 2023 Summary: Background: Heavy menstrual bleeding affects one in four women and negatively impacts quality of life. Ulipristal acetate is prescribed to treat symptoms associated with uterine fibroids.
Lucy H.R. Whitaker +19 more
doaj +2 more sources
Hepatic Safety Considerations in the Use of Ulipristal Acetate for Symptomatic Uterine Fibroids [PDF]
Therapeutics and Clinical Risk ManagementAnnika Semmler,1,2,* Maria E de Lange,2,* Joost PH Drenth,3 Niels S Vermeer,4 Pierre M Bet,4 Judith AF Huirne,1,2 Wouter JK Hehenkamp1,2 1Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands; 2Department of ...
Semmler A +6 more
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Ulipristal acetate simultaneously provokes antiproliferative and proinflammatory responses in endometrial cancer cells [PDF]
Heliyon, 2022 Ulipristal acetate (UPA), a selective progesterone receptor modulator, is used for the treatment of uterine fibroids and selectively inhibits the proliferation and inflammation of leiomyoma cells.
Ranka Kanda +8 more
doaj +2 more sources
Ulipristal Acetate Efficacy in a Patient with Symptomatic Fibroid and Concomitant Pulmonary Embolism [PDF]
Case Reports in Medicine, 2020 Ulipristal acetate (UPA) is an effective drug for the treatment of symptomatic uterine fibroids. The drug is highly effective in controlling bleeding control and in the recovery of anemia.
S. von Wunster +3 more
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Ulipristal acetate for Japanese women with symptomatic uterine fibroids: A double‐blind, randomized, phase II dose‐finding study [PDF]
Reproductive Medicine and Biology, 2020 Purpose A multicenter, randomized, double‐blind, placebo‐controlled trial was conducted to evaluate the efficacy, safety, and appropriate dose of ulipristal acetate (UPA) in Japanese women with symptomatic uterine fibroids (UFs).
Minoru Irahara +4 more
doaj +2 more sources
The Use of ulipristal acetate (Esmya) prior to laparoscopic myomectomy: Help or hindrance? [PDF]
Gynecology and Minimally Invasive Therapy, 2019 Introduction: The aim of this study was to assess the operative effects, both positive and negative, of pretreatment with ulipristal acetate (UPA) on laparoscopic myomectomy.
Rebecca Mallick +2 more
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Ulipristal acetate before in vitro fertilization: efficacy in infertile women with submucous fibroids [PDF]
Reproductive Biology and Endocrinology, 2020 Background The presence of submucous fibroids strongly impacts on IVF results, therefore, these patients should be considered for surgical or medical treatment.
Giuseppe Morgante +4 more
doaj +2 more sources
Ulipristal acetate as a treatment option for uterine fibroids. [PDF]
Prz Menopauzalny, 2017 Uterine fibroids are the most common benign uterine tumours. Clinical symptoms include abnormal bleeding, pelvic pressure, pelvic pain, infertility and obstetric complications. Approximately one third of women with fibroids will require treatment. The management also depends on the number, size, and location of the fibroids.
Piecak K +3 more
europepmc +3 more sources