Therapy with Ulipristal Acetate in a Hypertensive Patient [PDF]
Case Reports in Medicine, 2018 Ulipristal acetate (UPA) is a medical therapy for patients with symptomatic uterine fibroids. The drug has shown efficacy in the control of heavy menstrual bleeding and, as a consequence, in anaemia improvement.
A. Alcalde Dominguez +3 more
doaj +5 more sources
Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON): a randomised controlled phase III trialResearch in context [PDF]
EClinicalMedicine, 2023 Summary: Background: Heavy menstrual bleeding affects one in four women and negatively impacts quality of life. Ulipristal acetate is prescribed to treat symptoms associated with uterine fibroids.
Lucy H.R. Whitaker +19 more
doaj +2 more sources
Ulipristal acetate simultaneously provokes antiproliferative and proinflammatory responses in endometrial cancer cells [PDF]
Heliyon, 2022 Ulipristal acetate (UPA), a selective progesterone receptor modulator, is used for the treatment of uterine fibroids and selectively inhibits the proliferation and inflammation of leiomyoma cells.
Ranka Kanda +8 more
doaj +2 more sources
Ulipristal Acetate Efficacy in a Patient with Symptomatic Fibroid and Concomitant Pulmonary Embolism [PDF]
Case Reports in Medicine, 2020 Ulipristal acetate (UPA) is an effective drug for the treatment of symptomatic uterine fibroids. The drug is highly effective in controlling bleeding control and in the recovery of anemia.
S. von Wunster +3 more
doaj +2 more sources
Ulipristal acetate for Japanese women with symptomatic uterine fibroids: A double‐blind, randomized, phase II dose‐finding study [PDF]
Reproductive Medicine and Biology, 2020 Purpose A multicenter, randomized, double‐blind, placebo‐controlled trial was conducted to evaluate the efficacy, safety, and appropriate dose of ulipristal acetate (UPA) in Japanese women with symptomatic uterine fibroids (UFs).
Minoru Irahara +4 more
doaj +2 more sources
The Use of ulipristal acetate (Esmya) prior to laparoscopic myomectomy: Help or hindrance? [PDF]
Gynecology and Minimally Invasive Therapy, 2019 Introduction: The aim of this study was to assess the operative effects, both positive and negative, of pretreatment with ulipristal acetate (UPA) on laparoscopic myomectomy.
Rebecca Mallick +2 more
doaj +2 more sources
Ulipristal acetate before in vitro fertilization: efficacy in infertile women with submucous fibroids [PDF]
Reproductive Biology and Endocrinology, 2020 Background The presence of submucous fibroids strongly impacts on IVF results, therefore, these patients should be considered for surgical or medical treatment.
Giuseppe Morgante +4 more
doaj +2 more sources
Hepatic Safety Considerations in the Use of Ulipristal Acetate for Symptomatic Uterine Fibroids [PDF]
Therapeutics and Clinical Risk ManagementAnnika Semmler,1,2,* Maria E de Lange,2,* Joost PH Drenth,3 Niels S Vermeer,4 Pierre M Bet,4 Judith AF Huirne,1,2 Wouter JK Hehenkamp1,2 1Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands; 2Department of ...
Semmler A +6 more
doaj +2 more sources
Asian Journal of Medical Sciences, 2022 Background: Fibroid or uterine leiomyoma is the most common benign tumor of the uterus in the reproductive age group and found in one out of every four women.
Lipika Ghosh +2 more
doaj +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Nuclear hormone receptors
British Journal of Pharmacology, Volume 180, Issue S2, Page S223-S240, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and nearly 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +13 more
wiley +1 more source