Results 41 to 50 of about 349,354 (286)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
AIP Advances, 2015 In this paper, chaos control is proposed for the output- constrained system with uncertain control gain and time delay and is applied to the brushless DC motor. Using the dynamic surface technology, the controller overcomes the repetitive differentiation
Shaohua Luo, Zhiwei Hou, Zhong Chen
doaj +1 more source
Stochastic two-species mutualism model with jumps
Modern Stochastics: Theory and Applications, 2020 The existence and uniqueness are proved for the global positive solution to the system of stochastic differential equations describing a two-species mutualism model disturbed by the white noise, the centered and non-centered Poisson noises.
Olga Borysenko, Oleksandr Borysenko
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Dynamical Behavior of a Nonautonomous Stochastic Modified Bazykin Model
Journal of Chemistry, 2019 In this article, a nonautonomous stochastic modified Bazykin model is introduced. The positive solution is proved to be unique and global for any initial data via stochastic comparison theorem and Itô formula.
Zhangzhi Wei, Zheng Wu, Lianglong Wang
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Stability and ultimate boundedness of solutions of some third order differential equations with delay [PDF]
, 2016 This paper is devoted to study the boundedness, ultimate boundedness, and the asymptotic stability of solutions for a certain class of third-order nonlinear differential equations using Lyapunov’s second method.
Beldjerd, D., Remili, M.
core +1 more source
Stability and Ultimate Boundedness for Non- Autonomous System with Variable Delay [PDF]
, 2020 In this paper, we investigate proper sufficient conditions for the uniform stability (US) of the zero solution, and for the uniform boundedness (UB) as well as uniform ultimate boundedness (UUB) of all solutions of a certain system of nonlinear non ...
Tunc ̧, Cemil, M. Mahmoud, Ayman
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Stochastic Delay Population Dynamics under Regime Switching: Global Solutions and Extinction
Abstract and Applied Analysis, 2013 This paper is concerned with a delay Lotka-Volterra model under regime switching diffusion in random environment. By using generalized Itô formula, Gronwall inequality and Young’s inequality, some sufficient conditions for existence of global positive ...
Zheng Wu, Hao Huang, Lianglong Wang
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source