Results 41 to 50 of about 10,978,845 (289)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Influence of stress wave-induced disturbance on ultra-low friction in broken blocks
Deep rock mass tends to be broken into blocks when mining for materials deep below the surface. The rock layer of the roof of the mine can be regarded as a system of blocks of fractured rock mass.
Liping Li +5 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
To enhance the application of ultra-low frequency dielectric loss testing technology in evaluating cable insulation conditions and to improve the testing efficiency of ultra-low frequency dielectric spectroscopy, the dielectric properties of cross-linked
Haiyu SUN +5 more
doaj +1 more source
This paper proposes an I-shaped radial elastic metamaterial with ultra-low-frequency broadband characteristics and studies the propagation characteristics of elastic waves in their quasi-static state.
Haixia Liu, Weitao He, Lixia Li, Qi Jia
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Frequency Selective Rasorber With Low Insertion Loss and Ultra‐Broadband Scattering Reduction
This article proposes a dual‐polarization broadband frequency selective rasorber (FSR) based on a composite metasurface structure, achieving ultra‐wide absorption bands on both sides of the transmission band. The vertically stacked configuration consists
Ziming Yu +4 more
doaj +1 more source
Offshore wind platforms face critical low-frequency vibration challenges requiring advanced isolation solutions. This work develops a quadrilateral-shaped vibration isolation platform (QVIP) with a quasi-zero stiffness property for floating structures ...
Zhenbin Guo +3 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Células SRAM de ultra baixa tensão com polarização de substrato [PDF]
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia ElétricaEsta dissertação visa o estudo da célula SRAM de 6 transistores, utilizando tecnologia CMOS convencional, operando em ...
Lima, Alessandro de Souza
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