Results 31 to 40 of about 1,366,171 (283)

Accuracy Analysis of Measuring Cylindrical Surfaces with Complex Parameters Using Two-Dimensional Pseudo Lateral Shearing Interferometry

Photonics
Cylindrical surfaces with complex parameters (CSCP), including off-axis, aspheric, and other properties, constitute fundamental components within complex optical systems.
Le Zhao, Zhongming Zang, Siqi Zhang, Yang Chen, Yueqing Zheng, Zhitian Niu, Jing Yu, Weizhou Luo, Zhu Li, Ming Kong, Shiling Wang, Kuo Hai   +11 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Autostereoscopic 3D Measurement Based on Adaptive Focus Volume Aggregation

Sensors, 2023
Autostereoscopic three-dimensional measuring systems are a kind of portable and fast precision metrology instrument. The systems are based on integral imaging that makes use of a micro-lens array before an image sensor to observe measured parts from ...
Sanshan Gao, Chi Fai Cheung
doaj   +1 more source

Sub-surface damage issues for effective fabrication of large optics [PDF]

, 2008
A new ultra precision large optics grinding machine, BoX®has been developed at Cranfield University. BoX®islocated at the UK's Ultra Precision Surfaces laboratory at the OpTIC Technium.
P. Morantz, Walker, D., D. Walker, Shore, Paul, X. Tonnellier, G. Yu, A. Baldwin, R. Evans, Tonnellier, Xavier, P. Shore, Evans, R., Yu, G., Baldwin, A., Morantz, Paul   +13 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Research on the Influence of the Material Removal Profile of a Spherical Polishing Tool on the Mid-Spatial Frequency Errors of Optical Surfaces

Micromachines
Elastic spherical polishing tools effectively conform to the polishing surface and exhibit high efficiency in the removal of materials, so they are extensively used in the sub-aperture polishing stages of optical components.
Zhaohao He, Kuo Hai, Kailong Li, Jiahao Yu, Lingwei Wu, Lin Zhang, Xing Su, Lisheng Cai, Wen Huang, Wei Hang   +9 more
doaj   +1 more source

Characterization of Surface Topography Variation in the Ultra-Precision Tool Servo-Based Diamond Cutting of 3D Microstructured Surfaces

Micromachines, 2021
Previous models of the relative tool-work vibration are not generalized to represent the surface generation mechanism in the ultra-precision tool servo-based diamond cutting (UTSDC) of three-dimensional (3D) microstructured surfaces.
Wei Yuan, Chi-Fai Cheung
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Application of diamond based materials and surface microchannel fabricationtechnology in efficient heat dissipation

Jin'gangshi yu moliao moju gongcheng
With the rise of third-generation semiconductors, electronic devices are evolving towards high-power, miniaturization, and integration. Traditional heat dissipation technologies are no longer sufficient to meet the heat dissipation requirements of high ...
Shibo DENG, Yongqi XIA, Mingtao WU, Xiaobin YUE, Dajiang LEI   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source