Results 31 to 40 of about 203,243 (305)

Imaging performance of an ultra-precision machining-based Fresnel lens in ophthalmic devices.

open access: yesOptics Express, 2021
This study aims to resolve the trade-off between the constraints and capabilities of ultra-precision machining to achieve ophthalmic Fresnel lenses. A general Fresnel lens pattern has a narrow variable pitch and curved grooves.
V. Vu   +4 more
semanticscholar   +1 more source

Contrast Experiments in Dielectrophoresis Polishing (DEPP)/Chemical Mechanical Polishing (CMP) of Sapphire Substrate

open access: yesApplied Sciences, 2019
The broad applications of sapphire substrates in many fields warrants an urgent demand for a highly efficient and high precision polishing method for the sapphire substrates.
Tianchen Zhao   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Accuracy Analysis of Measuring Cylindrical Surfaces with Complex Parameters Using Two-Dimensional Pseudo Lateral Shearing Interferometry

open access: yesPhotonics
Cylindrical surfaces with complex parameters (CSCP), including off-axis, aspheric, and other properties, constitute fundamental components within complex optical systems.
Le Zhao   +11 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Autostereoscopic 3D Measurement Based on Adaptive Focus Volume Aggregation

open access: yesSensors, 2023
Autostereoscopic three-dimensional measuring systems are a kind of portable and fast precision metrology instrument. The systems are based on integral imaging that makes use of a micro-lens array before an image sensor to observe measured parts from ...
Sanshan Gao, Chi Fai Cheung
doaj   +1 more source

3D printing for ultra-precision machining: current status, opportunities, and future perspectives

open access: yesFrontiers of Mechanical Engineering
Additive manufacturing, particularly 3D printing, has revolutionized the manufacturing industry by allowing the production of complex and intricate parts at a lower cost and with greater efficiency.
Tao He   +11 more
semanticscholar   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Research on the Influence of the Material Removal Profile of a Spherical Polishing Tool on the Mid-Spatial Frequency Errors of Optical Surfaces

open access: yesMicromachines
Elastic spherical polishing tools effectively conform to the polishing surface and exhibit high efficiency in the removal of materials, so they are extensively used in the sub-aperture polishing stages of optical components.
Zhaohao He   +9 more
doaj   +1 more source

Characterization of Surface Topography Variation in the Ultra-Precision Tool Servo-Based Diamond Cutting of 3D Microstructured Surfaces

open access: yesMicromachines, 2021
Previous models of the relative tool-work vibration are not generalized to represent the surface generation mechanism in the ultra-precision tool servo-based diamond cutting (UTSDC) of three-dimensional (3D) microstructured surfaces.
Wei Yuan, Chi-Fai Cheung
doaj   +1 more source

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