Results 81 to 90 of about 2,692 (254)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Efeito do ultra-som na prevenção da hérnia incisional mediana em ratos

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Investigar se o ultra-som é capaz de evitar o aparecimento da hérnia incisional (HI), uma vez que o seu tratamento ainda é um problema não resolvido.
Renato Miranda de Melo, Cibele Marli Cação Paiva Gouvêa, Marcela Gimenez, Samanta Ferreira de Miranda, Alcino Lázaro da Silva   +4 more
doaj   +1 more source

EFEITO DE ONDAS ULTRA-SÔNICAS SOBRE A POPULAÇÃO DE Leuconostoc mesenteroides EM CALDO DE CANA-DE-AÇÚCAR THE EFFECT OF ULTRASOUND WAVES ON THE Leuconostoc mesenteroides POPULATION IN SUGARCANE JUICE

Pesquisa Agropecuária Tropical, 2007
<!-- @page { margin: 2cm } --> <p class="western" align="justify">No presente trabalho, irradiou-se caldo de cana-de-açúcar de primeira extração, com ondas ultra-sônicas, com o objetivo de controlar a bactéria <em>Leuconostoc ...
Manoel Soares Soares Júnior, Márcio Caliari, Raúl Jorge Castro Gomes   +2 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Medidas em diagramas tempo-frequência aplicado na caracterização de transições de estado com o uso de sinais ultra-sônicos espalhados do processo de coagulação sanguínea: Uma análise numérica.

Semina: Ciências Exatas e Tecnológicas, 2004
Este trabalho apresenta uma forma alternativa de análise do sinal obtido a partir do Método Ultra-Sônico (US) no estudo das alterações do plasma sanguíneo em processo de coagulação.
Carlos Dias Maciel, Lana Ribeiro da Fonseca Monteiro   +1 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

IDENTIFICAÇÃO DAS REGIÕES CORRESPONDENTES AOS LOBOS HEPÁTICOS DE CÃES POR MEIO DA ULTRA-SONOGRAFIA IDENTIFICATION OF CORRESPONDENT REGIONS OF THE HEPATIC LOBES IN DOGS BY ULTRASONOGRAPHY

Ciência Animal Brasileira, 2007
<p>O exame ultra-sonográfico mostra-se um método eficaz para a avaliação do fígado fornecendo dados sobre o seu tamanho, forma e alterações do parênquima.
Danielle Santos Martins, Carlos Eduardo Ambrósio, Adélia Hirsh, Karla Patrícia Cardoso Araújo, Dulcinéa Gonçalves Teixeira, Patrícia Reginato Facciotti, Annelise Baldacin Salgado, Maria Angélica Miglino, Arani Nanci Bonfim Mariana   +8 more
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source