Deresuscitation Informed by Ultrasound in Patients with Septic Shock Trial
Objectives The venous excess ultrasound (VExUS) can be used at the point‐of‐care to identify venous overload and end‐organ congestion in an effort to individually tailor resuscitation and deresuscitation in patients with septic shock. Methods We conducted a pilot randomized controlled feasibility trial of VExUS‐guided fluid management in adult patients
Brendan Innes +7 more
wiley +1 more source
Late-onset polyvinylpyrrolidone allergy in a long-term hemodialysis patient: a case report of dialysis hypotension and gastrointestinal symptoms. [PDF]
Narita T +10 more
europepmc +1 more source
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang +9 more
wiley +1 more source
Optimized Secretome Sample Preparation From High Volume Cell Culture Media for LC-MS/MS Proteomic Analysis. [PDF]
Baby Mattamana B +4 more
europepmc +1 more source
Effects of Mesenchymal Stem Cell‐Derived Exosomes on Lung Inflammation in a Murine Aspiration Model
This study assessed the effect of intravenous MSC‐derived exosomes on inflammatory lung injury in a rat model of LPS aspiration. Compared with LPS alone, MSC exosome treatment reduced histologic lung injury overall (significant group effect p = 0.02; linear trend p = 0.006) and significantly lowered Tnf gene expression on qRT‐PCR (p < 0.05).
Nogah Nativ‐Zeltzer +5 more
wiley +1 more source
Centrifugation-Assisted Ultrafiltration as an Innovative Methodology to Enhance Phenolic Compound Bioaccessibility and Bioavailability from Winery By-Product Extracts. [PDF]
Nieto JA +3 more
europepmc +1 more source
3D Polymeric Nanonetworks: From Self‐Assembly to Advanced Fabrication
This review provides the first systematic cross‐method comparison of fabrication techniques for 3D polymeric nanonetworks. It evaluates five key strategies—block copolymer self‐assembly, hyper‐crosslinking, template‐assisted methods, 3D printing, and nanolithography—across critical metrics including resolution, throughput, scalability, and material ...
Carlos G. Cobos +2 more
wiley +1 more source
Excess Conventional Ultrafiltration Volume Increases Risk for Postoperative Cardiac Surgery-Associated Acute Kidney Injury. [PDF]
Zhang H +11 more
europepmc +1 more source
Linear polyglycerol is proposed as a PEG‐alternative in mRNA‐loaded lipid nanoparticles to limit activation of anti‐PEG antibodies and reduce immunogenicity. Resulting nanoparticles may provide similar gene delivery capabilities, while preventing binding of anti‐PEG antibodies compared to PEGylated counterparts.
Yara Ensminger +8 more
wiley +1 more source

