Results 241 to 250 of about 117,512 (352)
Optimizing INFOGEST Digest Conditioning for Reliable In Vitro Assessment of Nutrient Bioavailability Using Caco-2 Cell Models. [PDF]
Camporesi G, Canzian C, Bordoni A.
europepmc +1 more source
ABSTRACT The protein sample preparation methods for shotgun proteomics are nowadays well‐established unlike the ones for whole protein analysis. The goal of my work has been to create a simple methodology which provides a single uncomplicated sample preparation tool for these two fields. Nowadays the bulk of proteomics work is done using detergents for
Alexandre Zougman
wiley +1 more source
Breaking barriers in peritoneal fibrosis: extracellular vesicles as promising diagnostic and therapeutic strategy. [PDF]
Zhong L, Zhang B, Li Y, Su B, Liao R.
europepmc +1 more source
Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain +4 more
wiley +1 more source
Alternative net ultrafiltration rate strategies in acute kidney injury: a feasibility randomized clinical trial. [PDF]
Murugan R +13 more
europepmc +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Discovery of Inhibitory Active Ingredients for α-Amylase and α-Glucosidase from Raspberry (<i>Rubus idaeus</i> L.) Stems and Leaves Guided by Affinity Ultrafiltration and UPLC-QTOF-MS/MS. [PDF]
Zhao W, Yang P, Chen M, Gu D, He D.
europepmc +1 more source
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said +10 more
wiley +1 more source

