Results 51 to 60 of about 229,915 (358)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Micromechanical approach for the analysis of wave propagation in particulate composites [PDF]

, 2019
Laser ultrasonic non-destructive testing is widely used for the inspection of mechanical structures. This method uses the propagation of ultrasonic guided waves (UGW) in the media.
Dinzart, Florence, Estrada, Octavio Andrés González, Rojas-Cristancho, Cristhian Fernando   +2 more
core   +5 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Detection of Dynamic Modulus and Crack Properties of Asphalt Pavement Using a Non-Destructive Ultrasonic Wave Method

Applied Sciences, 2019
Non-destructive ultrasonic testing has attained popularity due to its robustness and cost-effectiveness in monitoring the structural health and performance evaluation of pavements, thus replacing traditional methods.
Weiguang Zhang, Muhammad Arfan Akber, Shuguang Hou, Jiang Bian, Dong Zhang, Qiqi Le   +5 more
doaj   +1 more source

Improving the method of acoustic testing of new multilayer composite materials produced by explosion welding

Известия высших учебных заведений. Поволжский регион:Технические науки, 2023
Background. Multilayer metal materials have great prospects for application in various industries, such as nuclear, chemical and oil and gas. Proportionally, with the increase in the volume of production of these materials, there is an increase in the ...
K.D. Kulikov, A.V. Khorin, A.E. Rozen
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

A modular FPGA-based ultrasonic array system for applications including non-destructive testing [PDF]

, 2008
This paper reports work aimed at the development of an ultrasonic imaging system comprising modular, reprogrammable building blocks, or tiles, which can be customised for multiple applications, including and within non-destructive testing (NDT), by the ...
Afroukh, F., Cochran, S., Cumming, D.R.S., Saillant, J-F., Triger, S., Wallace, J., Wang, L.   +6 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Best Practices in Bolt Inspection Using Ultrasonic Testing

e-Journal of Nondestructive Testing
Ultrasonic testing (UT) is a widely adopted method for inspecting bolts, offering non-destructive testing and evaluation (NDE) of critical components in various industrial sectors.
Qaihri Wahab, Chin Kian Liew
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source