Results 241 to 250 of about 81,416 (305)

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

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Ultrasonic Aspiration Transducer

Radiology, 1972
Fluid-containing structures can be localized and aspirated by using a specially-designed ultrasonic transducer with a central hole. A needle is directed through the hole and into the tissue. The path of the needle tip can be followed ultrasonically as it enters the fluid. The same transducer is used to monitor the procedure continuously while the fluid
B B, Goldberg, H M, Pollack
openaire   +2 more sources

Micromachined Ultrasonic Transducers

2008
In this chapter the basic principles, the fabrication process, and some modelling approaches of the novel micromachined ultrasonic transducers (MUTs) are described. These transducers utilize the flex-tensional vibration of an array of micro membranes. They are usually called cMUT (capacitive Micromachined Ultrasonic Transducer) or pMUT (piezoelectric ...
Pappalardo M, CALIANO, Giosue', SAVOIA, ALESSANDRO STUART, Caronti A.   +3 more
openaire   +2 more sources

Split-mode ultrasonic transducer

The Journal of the Acoustical Society of America, 2013
A split-mode ultrasonic transducer is investigated in both theory and experiment. This transducer is a two-dimensional structure of periodically poled domains in a ferroelectric wafer with free surfaces. The acoustic vibrations are excited by a radio frequency electric current applied along the length of the wafer, which allows the basal-plane surfaces
Igor, Ostrovskii, Lucien, Cremaldi
openaire   +2 more sources

Ultrasonic Aspiration-Biopsy Transducer

Radiology, 1973
A specially designed ultrasonic aspiration-biopsy transducer (UABT) containing a central lumen was used as an aid in the aspiration of fluid-containing structures and the biopsy of solid tissue. Ultrasound provided an estimate of the subcutaneous depth of the tissues of interest, and, in the case of cystic masses, allowed an estimate of the volume of ...
B B, Goldberg, H M, Pollack
openaire   +2 more sources

Optimization of ultrasonic transducers

Ultrasonics, 1985
The so-called KLM-model for ultrasonic transducers is employed to optimize transducer design. Some new performance characteristics are defined which change monotonically with design parameters. These characteristics are based on the area of the envelope of the echo waveform produced by the transducer and of the corresponding amplitude spectrum.
J M, Thijssen, W A, Verhoef, M J, Cloostermans   +2 more
openaire   +2 more sources

Ultrasonic wave transducer system and ultrasonic wave transducer

The Journal of the Acoustical Society of America, 2003
There is disclosed an ultrasonic transducer system for harmonic imaging, comprising: an ultrasonic transducer comprising a transmitting ultrasonic vibrator for transmitting a fundamental ultrasound having a center frequency f0, and a receiving ultrasonic vibrator for receiving a harmonic signal having a center frequency nf0 (n is an integer of 2 or ...
Hideo Adachi, Katsuhiro Wakabayashi
openaire   +1 more source