Results 51 to 60 of about 193,905 (227)

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Subareolar breast abscess in male patients: a report of two patients with a literature review

Surgical Case Reports, 2017
Background Subareolar breast abscess (SBA) is a rare infectious disease of the breast in male patients. Case presentation Herein, we report two male patients with SBA.
Takashi Kazama, Isao Tabei, Chikako Sekine, Naotake Funamizu, Shinji Onda, Tomoyoshi Okamoto, Hiroshi Takeyama, Toshiaki Morikawa   +7 more
doaj   +1 more source

Pyometra and mammary gland tumor in a Beagle dog at the Veterinary Teaching Hospital of Brawijaya University, Malang, Indonesia

Ovozoa: Journal of Animal Reproduction, 2023
A 12-year-old Beagle dog weighing 7.7 kg was brought to the Brawijaya University Veterinary Teaching Hospital in a state of dehydration, lethargy, and jaundice. On the 2nd day of hospitalization, the dog had mucopurulent discharge from the vagina.
Nofan Rickyawan, Dian Vidiastuti, Karlina Karlina, Shelly Kusumarini   +3 more
doaj   +1 more source

Rat mammary carcinogenesis following neutron- or X-radiation [PDF]

, 1974
Female 61 to 63 - day - old Sprague-Dawley rats were exposed once to a single dose of either 0.43 - MeV neutrons or 250 - kVX - rays . For neutrons 23 rats were exposed in plastic tubes rotated around and 31 c m from a water-cooled tritium impregnated ...
Rossi, H. H., Mills, R. E., Kellerer, Albrecht M., Goodman, L. J., Rao, A. R., Bond, V. P., Brown, R. D., Shellabarger, C. J., Shanley, J. P.   +8 more
core   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source

Cellular and molecular effects of early pregnancy on mammary epithelial cell subpopulations in mice and their potential relevance for breast cancer protection [PDF]

, 2013
The breast cancer protective effect of an early pregnancy is well established in both humans and rodents, but the underlying mechanism is unclear. Since breast cancers are thought to originate from distinct mammary epithelial cell subtypes, we studied ...
Meier-Abt, Fabienne
core   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Axillary galactocele of ectopic breast: Ultrasound and mammography correlation

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2018
Ectopic or accessory breast tissue may occur anywhere along the milk line or mammary ridge extending from axilla to groin. The most common location of the ectopic breast is axilla.
Sakshi Daga, Suresh Phatak, Sheeba Khan, Shishir Rawekar   +3 more
doaj   +1 more source

The Automation of Breast Ultrasonography and the Medical Time Dedicated to the Method

Revista Brasileira de Ginecologia e Obstetrícia, 2023
In this integrative review, we aimed to describe the records of time devoted by physicians to breast ultrasound in a review of articles in the literature, in order to observe whether the automation of the method enabled a reduction in these values.
Katyane Larissa Alves, Ruffo Freitas Junior, Régis Resende Paulinelli, Marcus Nascimento Borges   +3 more
doaj   +1 more source

Imaging and Diagnostic Tools for Cetacean Mammary Gland Assessment: Challenges and Future Directions for Marine Mammal Pathology, Medicine and Research. [PDF]

J Mammary Gland Biol Neoplasia
Reproduction studies are important for the conservation of cetaceans (whales, dolphins, and porpoises) because they provide essential information for assessing populations and species dynamics, particularly in relation to the management of the diverse ...
Robles-Malagamba MJ, Gerussi T, Sánchez-Contreras GJ, Dean MN.   +3 more
europepmc   +2 more sources