Results 231 to 240 of about 2,378,727 (293)

Magneto‐Sono‐Enhanced Nanozyme Catalysis Drives ROS‐Mediated Pathogen Killing and Mitophagy‐Linked Inflammation Control in Bacterial Pneumonia

Advanced Science, EarlyView.
Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo, Yundi Wu, Shuai Zhang, Huanran Qu, Shiyang Shao, Jianqiang Chen, Xilong Wu   +6 more
wiley   +1 more source

Differentiating hepatic hemangiomas from hepatocellular carcinomas using Sonazoid-enhanced ultrasonography: a proposed two-step diagnostic algorithm. [PDF]

Ultrasonography
Han T, Hwang JA, Jeong WK, Han S, Choi SY, Gu K.   +5 more
europepmc   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

Advanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu, Zitian Zheng, Feiran Wang, Huanhuan Luo, Fei Ju, Yucheng Zhu, Zheng Zhou, Jie Sun, Zhenghui Qiu, Xiang Luo, Zhongzheng Jia, Jianquan Wang, Hongjie Huang, Bo Zhang   +13 more
wiley   +1 more source

Disappearing Colorectal Liver Metastases: Should the Treatment Sequence Be Reconsidered for Selected Lesions? [PDF]

Cancers (Basel)
Giacomoni A, Paterno M, Aseni P, Benedetti A, Calcagno P, Solcia M.   +5 more
europepmc   +1 more source

A Tumor‐Boundary Niche Enriched for PD‐1+CD8+T Cells and BTLA+B Cells Drives Resistance to Immunotherapy in NSCLC

Advanced Science, EarlyView.
A spatial niche composed of BTLA+B cells and CD8+T cells is enriched at the tumor boundary in non‐small cell lung cancer. Within this specialized niche, BTLA+B cells act as a dominant source of IL‐6, upregulating PD‐1 on CD8+T cells via STAT3 signaling.
Jiajuan Wu, Shiying Guo, Leilei Lv, Guiqin Fan, Yu Shen, Qiuxia Qu, Cheng Chen   +6 more
wiley   +1 more source

Ultrasound muscle geometry and malnutrition in community-dwelling older adults. [PDF]

J Nutr Health Aging
Abizanda Saro A, Reinioso Párraga P, González Ramírez A, Neira Álvarez M, López Jiménez E, Fernández González de la Riva M, Alonso Bouzón C, Chavero Carrasco V, Montemayor Galán G, Rodríguez Solís J, Alcantud Córcoles R, Ramírez Martín R, de Pablos Hernández C, Zambom-Ferraresi F, Dax Vásquez B, Sagüillo González PL, Morón Merchante I, García Molina R, Menéndez Colino R, Martínez Velilla N, Andrés Pretel F, Gómez Jiménez E, Sáez Blesa M, Cortés Zamora EB, Avendaño Céspedes A, Abizanda P.   +25 more
europepmc   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Discontinuing Surveillance of Low-Risk Branch-Duct Intraductal Papillary Mucinous Neoplasms in Routine Practice: An External Application of the "Trivial" Criteria and the Resources it Would Release in Fourteen Health Systems. [PDF]

United European Gastroenterol J
Ricci C, D'Ambra V, Casarotto M, Alberici L, Ingaldi C, Fichera M, Mosconi C, Migliori M, Casadei R.   +8 more
europepmc   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source