Results 61 to 70 of about 698,283 (284)

The value of ultrasonographic scoring method and nomogram in assessing cervical lymph node metastasis of papillary thyroid carcinoma

Thyroid Research
Background The preoperative cervical lymph node metastasis (CLNM) status in patients with papillary thyroid carcinoma (PTC) critically determines the type of lymph node dissection performed.
Liping Chen, Yan Chen, Zhengming Hu, Huali Cai, Xiaona Lin, Jieyu Zhong, Desheng Sun   +6 more
doaj   +1 more source

Overview of Strategies to Improve Therapy against Tumors Using Natural Killer Cell

Journal of Immunology Research, 2020
NK cells are lymphocytes with antitumor properties and can directly lyse tumor cells in a non-MHC-restricted manner. However, the tumor microenvironment affects the immune function of NK cells, which leads to immune evasion.
Chaopin Yang, Yue Li, Yaozhang Yang, Zhiyi Chen   +3 more
doaj   +1 more source

Sparsity-driven sparse-aperture ultrasound imaging [PDF]

, 2006
We propose an image formation algorithm for ultrasound imaging based on sparsity-driven regularization functionals. We consider data collected by synthetic transducer arrays, with the primary motivating application being nondestructive evaluation.
Cetin, Mujdat, Çetin, Müjdat
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Diagnostic performance of intestinal ultrasound compared with CT enterography in Crohn’s disease: single-center experience

Frontiers in Medicine
AimThis study aimed to clarify the diagnostic value of transabdominal bowel ultrasonography (TBUS) examination for identifying the location of Crohn’s disease (CD) lesions and their complications in relation to computed tomography enterography (CTE ...
Yuanzhu Zhao, Qiong Fu, Panpan Wang, Shuru Wei, Dan Liu   +4 more
doaj   +1 more source

Radiology [PDF]

, 2004
Radiology is the fastest developing field of medicine and these unprecedented advances have been mainly due to improving computer technology. Digital imaging is a technology whereby images are acquired in a computer format, so that they can be easily ...
Vassallo, Pierre
core  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Super-resolution ultrasound quantifying microvascular alterations for early detection of metastatic cervical lymph nodes: a prospective diagnostic study

Scientific Reports
To evaluate super-resolution ultrasound (SRUS) for characterizing microvascular morphology and hemodynamics in metastatic versus reactive cervical lymph nodes (LNs), with the aim of improving metastatic detection and reducing unnecessary biopsies.
Jun Zhang, Zhiyu Zhao, Xin Huang, Xingyue Huang, Yao Zhang, Yugang Hu, Qing Deng, Qing Zhou, Qing Zhou   +8 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source