Results 201 to 210 of about 131,304 (295)

Haemanthidine-Containing Alkaloid Fraction from Crinum scabrum as a Natural Therapeutics for Chagas Disease

ACS Omega
Jennifer Blandón Pardo, Lorraine Martins Rocha Orlando, Leonardo da Silva Lara, Mirian Claudia de Souza Pereira, Natália Ferreira de Sousa, Luciana Scotti, Marcus Tullius Scotti, Warley de Souza Borges   +7 more
doaj   +1 more source

The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu, Yang‐Shuai Wang, Chun‐Yang Shang, Ming Qi, Tong‐Chang Li, Li‐Xin Lian, Hai‐Quan Qiao   +6 more
wiley   +1 more source

Liuwei Dihuang pills attenuates cognitive dysfunction in <i>APP/PS1</i> mice through restoring mitochondrial homeostasis and activating the IRS/AKT/GSK3β insulin signaling pathway. [PDF]

Front Pharmacol
Song J, Yuan Y, Wang M, Li J, Ding R, Jia Y, Wang Z, Xie Z, Li Z, Zhang Z.   +9 more
europepmc   +1 more source

NETosis in the Kidney, Liver, and Lung of Mice With Cecal Ligation and Puncture‐Induced Sepsis and the Ameliorating Effects of Adipose‐Derived Stem Cell Exosomes

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced organ failure involves dysregulated neutrophil responses, including neutrophil extracellular trap (NET) formation, via NETosis. Exosomes generated from adipose‐derived stem cells (ADSCs) have shown potential in sepsis treatment. This study characterized organ‐specific NETosis in the kidney, liver, and lungs using a murine cecal ...
Shao‐Chun Wu, Tsu‐Hsiang Lu, Yi‐Chan Wu, Chia‐Wei Lin, Chia‐Wen Tsai, Ching‐Hua Hsieh   +5 more
wiley   +1 more source

Pharmacological activation of SIRT1 alleviates sepsis-associated acute kidney injury by improving renal mitochondrial energy metabolism. [PDF]

Ren Fail
Zhu R, Yang H, Liu L, Gao Y, Gao X.
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Activation of Nrf2 signaling and suppression of oxidative stress-induced neuronal apoptosis: mechanisms for baicalin capsules relieving diabetic encephalopathy. [PDF]

Front Pharmacol
Tian R, Zhou X, Pan J, Yu C, Lian X, Lei K, Liu J, Liu Y, Xi H, Luo L, Wen J.   +10 more
europepmc   +1 more source

Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1

Muscle &Nerve, EarlyView.
ABSTRACT Glutamine:fructose‐6‐phosphate transaminase 1 (GFPT1) catalyzes the first and rate‐limiting step of the hexosamine biosynthetic pathway (HBP) to generate UDP‐GlcNAc. GFPT1 exon 9 is specifically spliced in in striated muscles, which makes a long isoform of GFPT1 (GFPT1‐L).
Kinji Ohno, Mohammad Nazim, Ruchen Zhang, Paniz Farshadyeganeh, Mikako Ito, Bisei Ohkawara   +5 more
wiley   +1 more source

Correction for Chang et al., Plant pathogenic nematode exosomes remodel vector tracheae to enhance pathogen transmission. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Morphological and Ultrastructural Characterization of the Venom Apparatus of the Predatory Stink Bug, <i>Arma custos</i>. [PDF]

Insects
Wang Y, Gao P, Wu C, Wang W, Zhu J.
europepmc   +1 more source