Results 231 to 240 of about 135,815 (306)

Multi-omics analysis reveals gut microbiota-host metabolism-shell gland axis underlying eggshell deterioration in aged laying hens. [PDF]

Poult Sci
Zhao X, Liu Q, Tian Y, Cui X, Du Y, Yue Y, Lei X, Chen Z, Zhang F.   +8 more
europepmc   +1 more source

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

Pediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia, Xiaolin Ye, Zhaoxia Wang, Jie Wu   +3 more
wiley   +1 more source

Ultrastructure and Function of the Male Reproductive System in the Rotifer Asplanchnopus cf. multiceps (Rotifera: Monogononta). [PDF]

J Morphol
Araújo TQ, Wallace RL, Walsh EJ, Hochberg R.   +3 more
europepmc   +1 more source

A composite, host‐participatory haustorium links host compatibility to defence bifurcation in Alectra vogelii (Orobanchaceae)

PLANTS, PEOPLE, PLANET, EarlyView.
Parasitic weeds of the family Orobanchaceae are among the most damaging constraints on food production in the tropics, draining water and nutrients from their hosts and threatening the livelihoods of millions of smallholder farmers. Yellow witchweed (Alectra vogelii) can destroy entire legume harvests across sub‐Saharan Africa, where these crops are a ...
Hildah Kithinji, Guillaume Brun, Susann Wicke   +2 more
wiley   +1 more source

Ultrastructural diversity and subcellular organization of nigral Lewy pathology in Parkinson's disease. [PDF]

Nat Commun
Lewis AJ, van den Heuvel L, Di Fabrizio M, Bandelier K, Proniakova D, Burger D, Shafiei N, Ekundayo K, Offringa S, Huisman E, Bol JG, van de Berg WD, Stahlberg H.   +12 more
europepmc   +1 more source

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

Phytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo, Fansu Meng, Detang Li, Maciej Mazur, Alicia Marcelina Díaz García, Mulazim Hussain Asim, Zhong Chen, Yiqi Chen, Yixuan Lin, Zhenjiang Yang, Panpan Wang, Yu Cai   +11 more
wiley   +1 more source

NR4A1-Driven Granulosa Cell Ferroptosis Contributes to Obesity-Related Ovarian Dysfunction and Metformin-Mediated Ovarian Protection. [PDF]

FASEB J
Wang H, Wang C, Guo S, Yang G, Fang J, Hu J, Jiang R, Zhai J, Jin H, Song W, Shi S, Huang X, Qi L, Wu Z, Liu Y, Song N, Zhang X, Yao G.   +17 more
europepmc   +1 more source

Protosappanin A Alleviates Atherosclerosis by Regulating the MDM2/GPX4 Axis‐Mediated Endothelial Ferroptosis

Phytotherapy Research, EarlyView.
PTA alleviates atherosclerosis by regulating the MDM2/GPX4 axis‐mediated endothelial ferroptosis. ABSTRACT Endothelial ferroptosis is a crucial pathogenic driver of atherosclerosis (AS) progression. Protosappanin A (PTA), a bioactive compound from Caesalpinia sappan L., protects cardiovascular vessels by regulating ferroptosis.
Jiamei Fu, Lin Zhu, Wenwei Yang, Mengnan Li, Zhixin Wu, Shude Sun, Yabin Zhou   +6 more
wiley   +1 more source

Strain-Specific Effects of <i>Epichloë bromicola</i> Symbionts on Photosynthesis and Chloroplast Ultrastructure in <i>Hordeum bogdanii</i>. [PDF]

J Fungi (Basel)
Chen S, Liu X, Hu M, Teng T, Long F, Gao J, Bao G, Chen S.   +7 more
europepmc   +1 more source