Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Mitochondrial Transfer from Human Platelets to Rat Dental Pulp-Derived Fibroblasts in the 2D In Vitro System: Additional Implication in PRP Therapy. [PDF]
Nishiyama K+9 more
europepmc +1 more source
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang+9 more
wiley +1 more source
Plantar Ulcerative Lichen Planus as a Therapeutic Challenge: A Review of Literature. [PDF]
AlSulami M+5 more
europepmc +1 more source
Protective Effect of Epigallocatechin Gallate and Esculetin on Oxidative DNA Damage Induced by Psoralen Plus Ultraviolet-A Therapy [PDF]
Shoichi Tahara+3 more
openalex +1 more source
Picosecond measurements an Halorhodopsin of Halobacterium halobium [PDF]
Franz, M. A.+3 more
core +1 more source
Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells
Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella+9 more
wiley +1 more source
The Treatment of Pembrolizumab-Induced Pruritus with Topical Roflumilast Cream 0.3% Once Daily. [PDF]
Lomax L.
europepmc +1 more source
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani+11 more
wiley +1 more source
Successful repigmentation with ritlecitinib and combined home-based phototherapy in an intractable case of generalized vitiligo. [PDF]
Sun XK, Xu AE.
europepmc +1 more source