Results 21 to 30 of about 394 (142)
, 2019 Background: Coumarin and modified nitrogen heterocyclic nuclei show biological activity. Combining these into a hybrid molecule could lead to new pharmacological agents. A series of hybrid compounds combining coumarin and piperidine, piperazine, purine
Arkady O. Brysgalov +3 more
core +1 more source
Synthesis of umbelliferone derivatives in Escherichia coli and their biological activities [PDF]
Journal of Biological Engineering, 2017 La umbeliferona, también conocida como 7-hidroxicumarina, es un metabolito fenólico que se encuentra en muchas plantas familiares. Se ha demostrado que sus derivados tienen diversos efectos farmacológicos y quimiopreventivos en la salud humana. Se utilizaron una uridina difosfato glicosiltransferasa YjiC de Bacillus licheniformis DSM 13, una variante ...
Luan Luong Chu +6 more
openaire +4 more sources
Plant Biotechnology Journal, EarlyView.ABSTRACT The plant‐derived specialized metabolite montbretin A (MbA) is under development as an improved treatment for Type 2 diabetes, a worldwide epidemic. MbA is an acylated flavonol glycoside so far only found in small amounts in montbretia (Crocosmia × crocosmiiflora) corms.
Charlotte Hijmans +4 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.We utilized the leaf wastes of floriculture crops, namely Tagetes patula, Chrysanthemum grandiflorum, and Alstroemeria hybrida to determine their insecticidal potential against nymphs and adults of Aphis craccivora. Targeted and nontargeted metabolomics of extracts showed the presence of phenols and flavonoids, which corroborates the insecticidal ...
Aditya Singh Ranout +7 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.n‐hexane and EtOAc fractions of Convolvulus althaeoides aerial parts have potent cytotoxicity, significant antioxidant, and moderate anti‐inflammatory effects. These activities emphasize the potential role of this plant in cancer prophylaxis and treatment.
Ahmed R. Hassan +4 more
wiley +1 more source
Umbelliferone and Esculetin: Inhibitors or Substrates for Polyphenol Oxidases?
Biological and Pharmaceutical Bulletin, 2008 Recently, an interesting debate arose about the nature (substrate versus inhibitor) of esculetin, a coumarin derivative, for mushroom polyphenol oxidase (PPO). The present study examined the behavior of PPOs preparations from fungal and plant origin towards esculetin as a substrate. Both enzymes were able to oxidize esculetin though at a slow rate.
Sollai, F +4 more
openaire +3 more sources
Excited‐State Antiaromaticity Relief‐Guided Discovery of 7‐Hydroxycoumarins as Photoacid Catalysts
ChemCatChem, Volume 18, Issue 17, 14 September 2026.DFT and NICS studies are presented, in order to elucidate the relation of photoacidity with antiaromaticity relief of the excited state of 4‐substituted umbelliferone derivatives, leading to the experimentally optimum selection of photoacid catalysts for the acetalization reaction.
E. Alexandros Routsi +5 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.Chamomile (Matricaria chamomilla) extract significantly reduced oocyst shedding and intestinal lesions in immunosuppressed mice infected with Cryptosporidium parvum, while enhancing antioxidant defences (GPx, TAC). These findings suggest chamomile as a promising phytotherapeutic agent for cryptosporidiosis. ABSTRACT Background Cryptosporidiosis, caused
Kousha Kiani +3 more
wiley +1 more source