Results 101 to 110 of about 588,918 (412)
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Bifurcations of Umbilic Points and Related Principal Cycles [PDF]
, 2003 The simplest patterns of qualitative changes on the configurations of lines of principal curvature} around umbilic points on surfaces whose immersions into $\mathbb R^3$ depend smoothly on a real parameter (codimension one umbilic bifurcations) are described in this paper. Global effects, due to umbilic bifurcations, on these configurations such as the
arxiv +1 more source
Totally Umbilical Hypersurfaces of Product Spaces [PDF]
arXiv, 2021 Given a Riemannian manifold $M,$ and an open interval $I\subset\mathbb{R},$ we characterize nontrivial totally umbilical hypersurfaces of the product $M\times I$ -- as well as of warped products $I\times_\omega M$ -- as those which are local graphs built on isoparametric families of totally umbilical hypersurfaces of $M.$ By means of this ...
arxiv
Stem Cells International, 2015 This study is aimed at investigating whether human umbilical cord mesenchymal stem cell- (hucMSC-) derived exosomes (hucMSC-exosomes) have a protective effect on acute myocardial infarction (AMI).
Yuanyuan Zhao +7 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li +11 more
wiley +1 more source
Biology DirectBackground Doxorubicin (Dox) is associated with various liver injuries, limiting its clinical utility. This study investigates whether NSUN2 participates in Dox-induced liver injury and the associated molecular mechanism.
Yingying Huang +8 more
doaj +1 more source
On Pseudo-Umbilical Spacelike Submanifolds in Indefinite Space Form Mn+p p (c) [PDF]
arXiv, 2019 In the present note, first we derive an intrinsic inequality for Pseudo-umbilical spacelike submanifold in an indefinite space form. We use this inequality to show that such submanifold is totally geodesic. In the rest part of this paper, using a result of Aiyama [1], we prove that Pseudo-umbilical spacelike subamnifold is totally umbilical.
arxiv
The timing of umbilical cord clamping at birth: physiological considerations
Maternal Health, Neonatology and Perinatology, 2016 While it is now recognized that umbilical cord clamping (UCC) at birth is not necessarily an innocuous act, there is still much confusion concerning the potential benefits and harms of this common procedure.
S. Hooper +7 more
semanticscholar +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John +5 more
wiley +1 more source
Discover OncologyTrimethylamine-n-oxide (TMAO) is a metabolite of intestinal flora following the consumption of phosphatidylcholine-rich foods. Clinical cohort studies have shown that plasma TMAO may be a risk factor for cancer development, including hepatocellular ...
Chunfang Zhou +6 more
doaj +1 more source