Results 201 to 210 of about 30,258 (296)

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

British Journal of Pharmacology, EarlyView.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi, Annika A. Jüttner, Annique Claringbould, Rene de Vries, Ingrid M. Garrelds, Usha Musterd‐Bhaggoe, Bruno H. Stricker, Maryam Kavousi, A. H. Jan Danser, Fariba Ahmadizar, Anton J. M. Roks   +10 more
wiley   +1 more source

Hypercoiling and Single Umbilical Artery Associated With Fetal Placental Malperfusion and Growth Restriction: A Case Report. [PDF]

Clin Case Rep
Tanimura M, Yamagata T, Matsui M, Yamaoka Y, Ida K, Nakamura S, Tanaka M, Matsubara M.   +7 more
europepmc   +1 more source

Transient Hyperparathyroidism and Severe Intrauterine Osteopenia Linked to Novel Homozygous TRPV6 Deletion

Clinical Endocrinology, EarlyView.
ABSTRACT Context Placental calcium (Ca2+) transport is essential for foetal bone mineralisation and development, as well as for Ca2+ homoeostasis. Rare mutations in transient receptor potential vanilloid (TRPV) 6 of the infant cause insufficient maternal‐foetal Ca2+ transport through the placenta.
Teodora Grigore, Quinty Leusink, Femke Latta, Bram van der Eerden, Paul de Laat, Danielle van der Kaay, Joost Hoenderop   +6 more
wiley   +1 more source

Two- and three-dimensional high-frequency real-time ultrasonography for estimating gestational age and assessing Doppler flow changes in pregnant rats. [PDF]

Quant Imaging Med Surg
He J, Deng Z, Chen Q, Xian S, Yin T, Dai F, Huang J.   +6 more
europepmc   +1 more source

Characteristics of unilateral cerebral palsy according to gestational age at birth: A retrospective study

Developmental Medicine &Child Neurology, EarlyView.
Unilateral cerebral palsy (CP) affects 826 children in the Canadian CP Registry: 69% born at term, 15% 32 to 37 weeks, and 16% less than 32 weeks. Gestational age at birth did not affect impairments such as vision or hearing impairment, ambulation, seizures, or feeding difficulty.
Johanie Victoria Piché, Nafisa Hussein, Adam Kirton, Darcy Fehlings, Maryam Oskoui, Michael Shevell, Mary Dunbar   +6 more
wiley   +1 more source

Vasa previa with bipartite placenta and velamentous cord insertion. [PDF]

Radiol Case Rep
Hafsi M, Duvinage CR, Sassine S, Hamdan Y, Hassan H, Maalouf S, Devianne F.   +6 more
europepmc   +1 more source

MRI, Child Opportunity Index, and 4‐year cognitive outcome after neonatal encephalopathy

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To evaluate the association of neonatal magnetic resonance imaging (MRI) and Child Opportunity Index (COI) with 4‐year cognitive outcomes after neonatal encephalopathy. Method This was a cross‐sectional analysis of 4‐year outcomes (interquartile range [IQR] = 48–52 months) in a single‐center prospective cohort of term neonatal ...
Ashley M. Bach, Eun Song Song, A. James Barkovich, Matthew J. Barkovich, Elizabeth E. Rogers, Donna M. Ferriero, Hannah C. Glass, Dawn Gano   +7 more
wiley   +1 more source

An Update on Umbilical Cord Abnormalities and Associated Thrombosis: A Systematic Review. [PDF]

Clin Pract
La Verde M, Braca E, Cerillo A, Fatigati M, De Franciscis P, Pisani D, Fordellone M, De Simone M, Campobasso CP, Feola A.   +9 more
europepmc   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

Developmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa, Kirsi Mikkonen, Marjo Metsäranta, Sanna Toiviainen‐Salo, Sampsa Vanhatalo, Leena Lauronen, Päivi Nevalainen   +6 more
wiley   +1 more source

Aging mothers, failing placentas? Association between maternal age and placental perfusion in a low-resource setting. [PDF]

PLOS Glob Public Health
Eze IO, Nwagha UI, Eze SC, Abdul AE, Igboezue VC, Muhammed R.   +5 more
europepmc   +1 more source