Results 81 to 90 of about 58,515 (333)

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Effects of Resveratrol, Caffeic Acid Phenethyl Ester and Silibinin on Isolated Human Umbilical Artery

International Journal of Traditional and Complementary Medicine Research
Objective: The aim of this study was to compare the vasoactive effects of resveratrol, CAPE and silibinin on the basal tone and serotonin (5-HT) induced contractile responses of isolated human umbilical arteries.Material-Method: This study was approved ...
Ayşegül Arzum Karabaş, Ayşe Saide Şahin   +1 more
doaj   +1 more source

Structural plasticity and isolation of umbilical cord progenitor cells of agouti (Dasyprocta prymnolopha) raised in captivity

Semina: Ciências Agrárias, 2019
The agouti has been used as an experimental model in several studies focused on reproductive biology. The umbilical cord, an embryonic attachment that connects the foetus to the placenta, has been reported as an important anatomical site for obtaining ...
Maria Acelina Martins de Carvalho, Napoleão Martins Argôlo-Neto, Elís Rosélia Dutra de Freitas Siqueira Silva, Yulla Klinger de Carvalho Leite, Gerson Tavares Pessoa, Dayseanny de Oliveira Bezerra, Maíra Soares Ferraz, Airton Mendes Conde Júnior, Andressa Rêgo da Rocha   +8 more
doaj   +1 more source

Compensatory Feto-Placental Upregulation of the Nitric Oxide System during Fetal Growth Restriction [PDF]

, 2012
Background: Fetal Growth Restriction is often associated with a feto-placental vascular dysfunction conceivably involving endothelial cells. Our study aimed to verify this pathogenic role for feto-placental endothelial cells and, coincidentally ...
Begliuomini, Silvia, Boldrini, Antonio, Casarosa, Elena, Coceani, Flavio, Fink, Bruno, Genazzani, Andrea R., Ghirri, Paolo, Pisaneschi, Silvia, Ripoli, Andrea, Sanchez, Angel Matias, Simoncini, Tommaso, Strigini, Francesca A. L.   +11 more
core   +3 more sources

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Perinatal Prognosis of Pregnancies with Single Umbilical Artery in a Romanian Third-Level Unit [PDF]

, 2023
János Levente Turos, Emmanuel Ladanyi, Tamás Szabó, Béla Szabó   +3 more
openalex   +1 more source

Placental Transfusion for Asphyxiated Infants. [PDF]

, 2019
The current recommendation for umbilical cord management of non-vigorous infants (limp, pale, and not breathing) who need resuscitation at birth is to immediately clamp the umbilical cord.
Bava, Sunita, Katheria, Anup C, Lakshminrusimha, Satyan, Rich, Wade D   +3 more
core  

The effects of spinal anaesthesia for elective caesarean section on uterine and umbilical arterial pulsatility indexes in normotensive and chronic hypertensive pregnant women: a prospective, longitudinal study [PDF]

, 2014
BACKGROUND: Despite the known effects of neuraxial blockade on major vessel function and the rapid decrease in uterine vascular impedance, it is unclear how the blockade affects the utero-placental circulation in the near-term.
Almeida, H., Cerdeira, A., Gaio, R., Graça, H., Guedes, L., Guedes-Martins, L., Macedo, F., Saraiva, J.   +7 more
core   +3 more sources

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Sonographic diagnosis and clinical significance of umbilical arterial atresia

Saudi Pharmaceutical Journal, 2017
To evaluate the feasibility of antenatal sonographic diagnosis of umbilical arterial atresia and its clinical significance. Data of 5 cases with umbilical arterial atresia diagnosed in our hospital were studied retrospectively.
Jinhe Ren
doaj   +1 more source