Results 91 to 100 of about 93,775 (303)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli   +12 more
wiley   +1 more source

Alterations in maternal cardiovascular parameters and their impact on uterine and fetal circulation in hypertensive pregnancies and fetal growth restriction

open access: yesInternational Journal of Cardiology. Cardiovascular Risk and Prevention
Objective: To examine potential alterations in maternal cardiovascular parameters in hypertensive pregnancies with or without fetal growth restriction (FGR) in comparison to uncomplicated normotensive pregnancies, and to determine the correlation between
Tatjana Maseliene   +5 more
doaj   +1 more source

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]

open access: yes, 2019
PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ   +7 more
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

open access: yesAdvanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo   +19 more
wiley   +1 more source

PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells [PDF]

open access: yes, 2019
Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR).
Althoff, Till F.   +14 more
core   +1 more source

Vascularized Cardiac Tissue Engineering: From Advances in Biofabrication to Translational Applications

open access: yesAdvanced Science, EarlyView.
This review presents a process‐oriented framework for vascularized cardiac tissue engineering, highlighting how the coordinated design of cells, biomaterials, and biofabrication strategies enables the functional development or vascularized myocardium for disease modelling and drug discovery.
Yang Liu   +9 more
wiley   +1 more source

Tracheal suctioning improves gas exchange but not hemodynamics in asphyxiated lambs with meconium aspiration. [PDF]

open access: yes, 2015
BackgroundCurrent neonatal resuscitation guidelines recommend tracheal suctioning of nonvigorous neonates born through meconium-stained amniotic fluid.MethodsWe evaluated the effect of tracheal suctioning at birth in 29 lambs with asphyxia induced by ...
Gugino, Sylvia F   +7 more
core  

High Glucose, But Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells [PDF]

open access: yes, 2015
Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases.
Aswin, S. (Soedjono)   +3 more
core   +2 more sources

Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi   +9 more
wiley   +1 more source

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