Results 51 to 60 of about 55,562 (305)

Two‐Photon Polymerized Microvascular Environments for Multicellular Modeling of the Blood–Brain Tumor Barrier

open access: yesAdvanced Materials Technologies, EarlyView.
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin   +9 more
wiley   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha   +13 more
wiley   +1 more source

Ductus Venosus Doppler S/D Value Adjusted Alfa Fetoprotein Levels to Decrease False Positive Rates

open access: yesGynecology Obstetrics & Reproductive Medicine, 2013
OBJECTIVE: Fetal liver is mostly perfused by umbilical vein via ductus venosus and AFP is synthesized and secreted from fetal liver. In this study we tried to determine the effect of ductus venosus and umbilical blood flow on serum AFP levels STUDY ...
Alptekin Tosun   +3 more
doaj  

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu   +23 more
wiley   +1 more source

The Role of Uterine and Umbilical Arterial Doppler in High-risk Pregnancy: A Prospective Observational Study from India

open access: yesClinical Medicine Insights: Reproductive Health, 2015
Aim To study the role of Doppler imaging in prediction of high-risk pregnancies and their outcomes. Methods and Material This prospective study in a setup of tertiary-level care center includes 500 high-risk pregnant women from rural and urban sectors ...
Teena Nagar   +5 more
doaj   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Single Umbilical Artery

open access: yesInternational Journal of Women’s Health Care, 2016
The Umbilical Artery Unica is found in 0.2 to 1.1% of all fetuses. Their presence of AOU in itself does not cause any harm to the fetus and newborn. Sometimes, however, this abnormality occurs associated with chromosomal abnormalities and other abnormalities Structural.
D’Agati Alfio   +4 more
  +5 more sources

Prenatal Diagnosis of Umbilical Cord Ulcer: A Report of Two Cases

open access: yesCase Reports in Obstetrics and Gynecology, 2019
Umbilical cord ulcer is related to fetal intestinal atresia or meconium; perforation of the ulcer causes fetal deterioration leading to fetal and neonatal death owing to fetal hemorrhage.
Daisuke Katsura   +8 more
doaj   +1 more source

Doppler ultrasound hemodynamic assessment in preeclampsia

open access: yesMedical Journal of Babylon, 2018
Background: Preeclampsia (PE) is the main factor in maternal mortality across the world, affecting 5%–8% of pregnant women. The impairment in placental perfusion due to vascular abnormalities leads to clinical presentations and is detectable by Doppler ...
Azad Saleem Hassan   +1 more
doaj   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

open access: yesAdvanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang   +11 more
wiley   +1 more source

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