Results 91 to 100 of about 3,681,773 (193)

Effects of 14 days of head‐down bed rest with or without exercise, and subsequent recovery on bone turnover, density and structure in older adults

Experimental Physiology, EarlyView.
Abstract Bed rest accelerates bone loss and may exacerbate skeletal fragility. This study examined the effects of 14 days of head‐down tilt bed rest (HDBR) with or without exercise, and subsequent recovery, on bone turnover, density and structure in older adults. Twenty‐two healthy older adults (55–65 years) completed the HDBR protocol.
Guy Hajj‐Boutros, Andréa Faust, Carmelo Mastrandrea, Vita Sonjak, Dounia Rouabhia, Gustavo Duque, Richard Kremer, Stéphanie Chevalier, Julie Lacombe, Mathieu Ferron, Tyler A. Churchward‐Venne, José A. Morais   +11 more
wiley   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Prospective study on the sonographic Evaluation of umbilicalcord coiling Index in late second trimester and its Association with perinatal outcome [PDF]

, 2013
INTRODUCTION: The umbilical cord is the major feto maternal unit that provides communication between the placenta and fetus. It is the life line of the fetus as it supplies water, nutrients and oxygen.
Gayathri, N
core  

Human placental transfer of xenobiotics in health and disease: New approach methodologies for developmental and reproductive toxicology testing and mathematical modelling

The Journal of Physiology, EarlyView.
Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley   +1 more source

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell, Andrew C. Povey, Edward D. Johnstone, Peter T. Ruane   +3 more
wiley   +1 more source

Umbilical cord coiling index for the prediction of adverse pregnancy outcomes: a meta-analysis and sequential analysis

, 2019
Purpose: To evaluate the potential association of abnormal cord coiling with adverse pregnancy outcomes. Materials and methods: We used the Medline (1966–2018), Scopus (2004–2018), Clinicaltrials.gov (2008–2018), Embase (1980–2018), Cochrane Central ...
Paraskevi Kotrogianni (6521675), Diamanto Koutaki (6521678), Vasilios Pergialiotis (5432684), Georgios Daskalakis (5432681), Evangelos Christopoulos-Timogiannakis (6521681), Nikolaos Papantoniou (779637)   +5 more
core   +1 more source

Second Trimester Antenatal Umbilical Coiling Index and Its Doppler Flow Characteristics and Perinatal Outcome: A Prospective study [PDF]

, 2019
OBJECTIVE: To study correlation between antenatal Umbilical Cord Coiling Index (UCI) and umbilical vein blood flow and perinatal outcome. METHODS: UCI and umbilical vein blood flow were determined in 200 antenatal women with by ultrasonography and ...
Sharmila, S Vandhana
core  

Annexin V‐Functionalized Injectable Calcium‐Deficient Hydroxyapatite for Extracellular Vesicles Binding and Controlled Release

Journal of Biomedical Materials Research Part A, Volume 114, Issue 10, October 2026.
ABSTRACT Calcium phosphates alone have a limited induction potential in challenging bone conditions, necessitating strategies that enhance cellular responses and matrix‐related processes. An injectable formulation combining calcium‐deficient hydroxyapatite (CDHA) with mesenchymal stem cell‐derived extracellular vesicles may present a promising approach
Eda Ciftci, Sefa Burak Cam, Feza Korkusuz, Emre Erdem, Feray Bakan Misirlioglu, Petek Korkusuz   +5 more
wiley   +1 more source

A Reproducible MRI‐Based Pipeline for Longitudinal Tracking of Laser‐Assisted Bioprinted Cells in Three‐Dimensional Constructs

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Laser‐assisted bioprinting was used to deposit iron oxide‐labelled endothelial cells in predefined patterns onto SCAP‐seeded gelatin biopapers to assemble multilayer constructs of increasing thickness. T2*‐weighted MRI monitored constructs for up to 35 days.
Mina Medojević, Charles Handschin, Ayako Washio, Malou Lea, Laurence Dallet, Aleksandar Jakovljević, Emeline J. Ribot, Olivia Kérourédan   +7 more
wiley   +1 more source