Results 141 to 150 of about 730,128 (402)

Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]

open access: yes, 2013
The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M.   +7 more
core  

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo [PDF]

open access: yes, 2017
Human umbilical cord blood (CB) has attracted much attention as a reservoir for functional hematopoietic stem and progenitor cells, and, recently, as a source of blood-borne fibroblasts (CB-BFs). Previously, we demonstrated that bone marrow stromal cell (
Biondi, Andrea   +11 more
core   +2 more sources

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

A sustained decrease in the systolic/diastolic ratio may be a sign of severe adverse events in the umbilical cord: a report of eight cases

open access: yesJournal of International Medical Research
A high systolic/diastolic (S/D) ratio of umbilical cord blood is a manifestation of intrauterine hypoxia. However, the clinical significance of a persistently decreased S/D ratio of umbilical cord blood has not been reported.
Yan-Jing Zeng   +3 more
doaj   +1 more source

Current Perspectives of Prenatal Sonographic Diagnosis and Clinical Management Challenges of Complex Umbilical Cord Entanglement

open access: yesInternational Journal of Women's Health, 2021
David M Sherer, Crystal Roach, Sarin Soyemi, Mudar Dalloul The Division of Maternal-Fetal Medicine, The Department of Obstetrics and Gynecology, State University of New York (SUNY), Downstate Health Sciences University, Brooklyn, NY, USACorrespondence ...
Sherer DM, Roach C, Soyemi S, Dalloul M
doaj  

A Simple Method to Isolate and Expand Human Umbilical Cord Derived Mesenchymal Stem Cells: Using Explant Method and Umbilical Cord Blood Serum

open access: yesInternational Journal of Stem Cells, 2017
Background and Objectives Mesenchymal stem cells (MSCs) are multipotent stem cells that can be isolated from umbilical cords and are therapeutically used because of their ability to differentiate into various types of cells, in addition to their ...
G. Hassan   +3 more
semanticscholar   +1 more source

Development of clinical sign-based scoring system for assessment of omphalitis in neonatal calves [PDF]

open access: yes, 2018
Omphalitis contributes significantly to morbidity and mortality in neonatal calves. Diagnosis of omphalitis is based on the local signs of inflammation—pain, swelling, local heat and purulent discharge. An abattoir trial identified an optimal, sign-based,
Steerforth, D, Van Winden, S C L
core   +1 more source

Covalent Peptide‐Graphene Conjugates for Enhanced Cell Spreading, Osteogenic Differentiation, and Angiogenesis in Bone Defects

open access: yesChemBioChem, EarlyView.
The three peptides RGD, DGEA, and KKGHK are covalently attached to the 2D nanomaterial graphene oxide (GO) to create new biomaterials for the treatment of severe bone injuries. These GO modifications improve cell spreading, stem cell differentiation into bone cell types, and formation of blood vessel‐like structures.
Michelle E. Wolf   +4 more
wiley   +1 more source

Predicting Maternal and Fetal Exposures of Elexacaftor–Tezacaftor–Ivacaftor during Pregnancy through Physiologically Based Pharmacokinetic Models

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The use of elexacaftor/tezacaftor/ivacaftor (ETI) has been associated with increased fertility in women with cystic fibrosis (CF) and is increasingly used during pregnancy to support both maternal and fetal health. However, little is known about the pharmacokinetics (PK) of ETI during pregnancy, which is crucial for optimizing its efficacy and safety ...
Eunjin Hong   +8 more
wiley   +1 more source

Umbilical Cord Blood NOS1 as a Potential Biomarker of Neonatal Encephalopathy

open access: yesFrontiers in Pediatrics, 2017
BackgroundThere are no definitive markers to aid in diagnosis of neonatal encephalopathy (NE). The purpose of our study was (1) to identify and evaluate the utility of neuronal nitric oxide synthase (NOS1) in umbilical cord blood as a NE biomarker and (2)
Jun Lei   +20 more
doaj   +1 more source

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