Secondary Site Ligand for Integrin αVβ3 Enables Targeted mRNA Delivery
Non‐orthosteric, low‐affinity ligands for integrin αVβ3, identified by fragment screening, achieve superselective nanoparticle targeting (ακ ≈ 3) of αVβ3‐overexpressing endothelial cells. Unlike traditional arginine–glycine–aspartate decorated particles, these fragment‐functionalized LNPs discriminate cells by receptor density and deliver mRNA to ...
Sebastian Bayer +7 more
wiley +2 more sources
A taxonomic revision of the land snail genus <i>Acinolaemus</i> F. G. Thompson & Upatham, 1997 (Gastropoda, Eupulmonata, Hypselostomatidae), with notes on <i>Clostophis</i> W. H. Benson, 1860 species from Cambodia, Thailand, and Vietnam. [PDF]
Gojšina V +6 more
europepmc +1 more source
We observed a negative effect of brachycephalic obstructive airway syndrome (BOAS) in a staggered manner based on the severity of the condition on respiratory and cardiac patterns, glycemia, acid–base balance, fetal growth, and uterine artery hemodynamics, thus requiring adaptations within the fetal–placental unit. Severely affected bitches had uterine
Roberto Rodrigues da Rosa Filho +4 more
wiley +1 more source
Defining female gluteal geometry for preoperative planning in body contouring. [PDF]
Raposio E, Bertulla E.
europepmc +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Prune Belly Syndrome Complicated by Congenital Urinary Fistula in a Neonate: A Case Report from Hargeisa Group Hospital, Hargeisa Somaliland. [PDF]
Ali AMH +3 more
europepmc +1 more source
Lysyl oxidase crosslinking of type I collagen decreases neutrophil extravasation through an endothelium during the initial response to P. aeruginosa. This decrease in extravasation is likely due to the increase in VE‐cadherin expression between endothelial cells seeded on LOX‐crosslinked collagen hydrogels.
Christopher J. Calo +7 more
wiley +1 more source
Persistent umbilical discharge beyond the neonatal period due to patent urachus in an infant managed in a resource-limited setting: a case report. [PDF]
Musse AI +5 more
europepmc +1 more source

