Results 71 to 80 of about 5,050,821 (258)
Automatic Generation of Test Cases from UML Models
CLEI Electronic Journal, 2018 [Context] The growing demand for high-quality software has caused the industry to incorporate processes to enable them to comply with these standards, but increasing the cost of development.
Constanza Pérez, Beatriz Marín
doaj +1 more source
Can unsupervised machine learning gain new insights into urodynamic pressure flow pattern analysis?
BJU International, EarlyView.Objectives To explore the use of unsupervised machine learning (UML) to analyse segments of the pressure flow study (PFS) curve after maximum flow, and subsequently to analyse the urodynamic and patient characteristics of men in the detected clusters. Subjects and Methods In this study, we considered 1650 PFSs of men with lower urinary tract symptoms ...
Wouter van Dort +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz +8 more
wiley +1 more source
An Object Oriented Model of a Railway Safety-Related Control System
Communications, 2002 There is a variety of methods and formalisms usable for writing specifications of railway interlocking and signalling systems or their subsystems. To write a consistent technical specification means to make a model with a required level of precision ...
Karol Rastocny +2 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez +13 more
wiley +1 more source
ReMoFP: A Tool for Counting Function Points from UML Requirement Models [PDF]
, 2011 Vitor A. Batista +5 more
openalex +1 more source
Human FASTK preferentially binds single‐stranded and G‐rich RNA
The FEBS Journal, EarlyView.Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Recent studies emphasize alternative functions of FTH1 relevant for nuclear processes, such as transcriptional regulation. This study shows a novel FTH1/BRD2 association in non‐small cell lung carcinoma (NSCLC). This nuclear interaction affects BRD2 protein stability in aggressive NSCLC cells.
Stefania Scicchitano +9 more
wiley +1 more source
The FEBS Journal, EarlyView.We investigated the role of the signal regulatory protein alpha (SIRPα)/CD47 axis in phagocytosis by disrupting the SIRPA gene in the THP‐1 cell line. The SIRPα KO THP‐1 cells retained their monocyte and macrophage characteristics similar to their wild‐type (WT) counterparts.
Saitong Muneekaew +5 more
wiley +1 more source
Transforming UML 'Collaborating' Statecharts for Verification and Simulation [PDF]
Journal of Systemics, Cybernetics and Informatics, 2003 Due to the increasing complexity of real world problems, it is costly and difficult to validate today's software-intensive systems. The research reported in the paper describes our experiences in developing and applying a set of methodologies for ...
Patrick O. Bobbie +2 more
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