Results 81 to 90 of about 5,155,579 (288)
Small Science, EarlyView.Fluorescent dye labeling enables nanoparticle imaging but may subtly alter their surface chemistry and biological behavior. This study compares dye‐labeled and unlabeled cerium oxide nanozymes, revealing changes in cellular uptake kinetics without affecting their final intracellular fate. Combined fluorescence and label‐free electron microscopy imaging
Kanika Dulta +3 more
wiley +1 more source
Automatic Generation of Test Cases from UML Models
CLEI Electronic Journal, 2018 [Context] The growing demand for high-quality software has caused the industry to incorporate processes to enable them to comply with these standards, but increasing the cost of development.
Constanza Pérez, Beatriz Marín
doaj +1 more source
Systems Engineering, EarlyView.ABSTRACT System of Systems (SoS) environments are inherently complex, involving numerous operationally and managerially independent component systems with hidden interdependencies and frequent interactions based on unstructured data. In this paper, we propose using graphical Retrieval‐Augmented Generation (GraphRAG), a tool that combines large language
Yinchien Huang +2 more
wiley +1 more source
Identification of Missing Knowledge in MBSE System Models Using Graph‐Based Machine Learning
Systems Engineering, EarlyView.ABSTRACT The design and development of complex aerospace systems pose significant challenges due to their growing complexity. Iterative design processes, guided by formal specifications, strive to refine initially vague characteristics through multiple stages.
Esma Karagoz +2 more
wiley +1 more source
Mission Aware Cyber‐Physical Security
Systems Engineering, EarlyView.ABSTRACT Perimeter cybersecurity, while essential, has proven insufficient against sophisticated, coordinated, and cyber‐physical attacks. In contrast, mission‐centric cybersecurity emphasizes finding evidence of attack impact on mission success, allowing for targeted resource allocation to mitigate vulnerabilities and protect critical assets.
Georgios Bakirtzis +3 more
wiley +1 more source
An Object Oriented Model of a Railway Safety-Related Control System
Communications, 2002 There is a variety of methods and formalisms usable for writing specifications of railway interlocking and signalling systems or their subsystems. To write a consistent technical specification means to make a model with a required level of precision ...
Karol Rastocny +2 more
doaj +1 more source
A Bibliometric Review of the INCOSE's Model‐Based Systems Engineering Roadmap
Systems Engineering, EarlyView.ABSTRACT Over the past decade, model‐based systems engineering (MBSE) has gained attention as an approach for managing system complexity, offering a shift from a document‐based to a model‐based approach. The International Council on Systems Engineering (INCOSE) sparked increasing interest when it introduced MBSE and its roadmap as part of its systems ...
Marjolein Antoinette Jannyne Velthuizen +2 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz +8 more
wiley +1 more source
Embedded SW Design Space Exploration and Automation using UML-Based Tools [PDF]
, 2007 Flávio Rech Wagner, Luigi Carro
openalex +1 more source
British Journal of Pharmacology, EarlyView.The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez +13 more
wiley +1 more source