Results 81 to 90 of about 5,050,821 (258)

USING UML SCENARIOS IN B2B SYSTEMS

open access: yesInternational Islamic University Malaysia Engineering Journal, 2010
Scenarios has become a popular technique for requirements elicitation and specification building. Since scenarios capture only partial descriptions of the system behavior, an approach for scenario composition and/or integration is needed to produce more ...
A. Jakimi   +4 more
doaj   +1 more source

Mechanism of cyanobacterial ferredoxin‐dependent flavin thioredoxin reductase reveals thiolate‐FAD charge transfer and catalytic asymmetry in a homodimer

open access: yesThe FEBS Journal, EarlyView.
Ferredoxin‐dependent flavin thioredoxin reductases (FFTRs) regenerate reduced thioredoxin, sustaining dithiol–disulfide exchange reactions that regulate protein activity in select organisms. In cyanobacterial FFTRs, we describe the formation of a thiolate–flavin charge transfer complex, asynchronous reduction of the two FAD cofactors within the ...
Martha Minjarez‐Saenz   +8 more
wiley   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

open access: yesThe FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini   +6 more
wiley   +1 more source

Runtime and Design Time Completeness Checking of Dangerous Android App Permissions Against GDPR

open access: yesIEEE Access
Data and privacy laws, such as the GDPR, require mobile apps that collect and process the personal data of their citizens to have a legally-compliant policy.
Ryan Mcconkey, Oluwafemi Olukoya
doaj   +1 more source

Generating Use Case Models from Arabic User Requirements in a Semiautomated Approach Using a Natural Language Processing Tool

open access: yesJournal of Intelligent Systems, 2015
Automated software engineering has attracted a large amount of research efforts. The use of object-oriented methods for software systems development has made it necessary to develop approaches that automate the construction of different Unified Modeling ...
Arman Nabil, Jabbarin Sari
doaj   +1 more source

Butyrate suppresses mucosal inflammation in inflammatory bowel disease primarily through HDAC3 inhibition in monocytes and macrophages

open access: yesThe FEBS Journal, EarlyView.
Butyrate mitigates intestinal inflammation in IBD. It does so primarily by suppressing pro‐inflammatory cytokines and costimulatory molecules in activated monocytes and macrophages, concomitant with enhancing pathogen clearance. In human colonic organoids, butyrate promotes epithelial expression of key genes involved in barrier function and immune ...
Daniela Parada‐Venegas   +16 more
wiley   +1 more source

Developing an Automated Model-Based Software Testing Tool From the Design Phase

open access: yesIEEE Access
Software testing involves a number of labor-intensive tasks that, to save resources, should be automated. Model-based software testing is one of the most widely used methods of software quality assurance in the business world is model-based software ...
Rasha Gh. Alsarraj   +2 more
doaj   +1 more source

Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein

open access: yesThe FEBS Journal, EarlyView.
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy