Results 41 to 50 of about 42,799 (304)

The Sustainable Development Goals Promise and Beyond [Elektronisk resurs] [PDF]

Referred to as comprehensive, universal, anthropocentric, and utopian, the Sustainable Development Goals (SDGs) have been unanimously embraced by United Nations member states in 2015, signifying a worldwide pledge toward specific objectives to accomplish
Swain, Ranjula Bali,, Bali Swain, Ranjula,, Bali Swain, Ranjula, Dobers, Peter, Dobers, Peter,   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Defining Spatial Priorities for Irrigation Development Using the Soil Conservation and Water Use Efficiency Criteria

Agronomy, 2019
This paper presents a methodology for defining spatial priorities for irrigation development in Vojvodina Province (Serbia). The purpose of the methodology is to take into account several UN Sustainable Development Goals and to try to minimize land ...
Atila Bezdan, Bosko Blagojevic, Milica Vranesevic, Pavel Benka, Radovan Savic, Jovana Bezdan   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Global Challenge and Re-Evaluation of Ecological Tourism in Line With Sustainable Development Goals

, 2021
In the 2030 Agenda for Sustainable Development adopted by the UN General Assembly on 5 September 2015, 17 targets were set in line with the Sustainable Development Targets.
Yilmaz, Gul, Gul Yilmaz
core   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

The Impact of Corporate Social Responsibility on Economic Growth in the Region

Вестник Российского экономического университета имени Г. В. Плеханова, 2022
The article studies problems of civilization development, which implies the conflict of interests of business proprietors, big multinational corporations and society urge towards sustainable development.
N. S. Bezuglaya
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Organic Pig Farming in Europe: Pathways, Performance, and the United Nations Sustainable Development Goals (SDGs) Agenda

Animals
Organic pig farming in Europe is endorsed as a promising route to more sustainable livestock production, but its ultimate contribution to the United Nations (UN) Sustainable Development Goals (SDGs) is a contested matter.
Vasileios G. Papatsiros, Konstantina Kamvysi, Lampros Fotos, Nikolaos Tsekouras, Eleftherios Meletis, Maria Spilioti, Dimitrios Gougoulis, Terpsichori Trachalaki, Anastasia Tsatsa, Georgios I. Papakonstantinou   +9 more
doaj   +1 more source

Crop rotation and management tools for every farmer?

Smart Agricultural Technology, 2023
Providing crop rotation and management (CRM) tools for every farmer worldwide might be the breakthrough in solving the UN sustainable development goal (SDG) of zero hunger.
Julius Schöning, Paul Wachter, Dieter Trautz   +2 more
doaj   +1 more source