Results 191 to 200 of about 573,262 (315)
Advanced Functional Materials, EarlyView.We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
[Patient complaints in primary care in a Spanish region (2018-2024): A quantitative analysis]. [PDF]
Aten PrimariaPérez-Jiménez A +2 more
europepmc +1 more source
Situación epidemiológica del síndrome pulmonar por hantavirus (SPH). Paraguay 2000-2004
, 2008 El Síndrome Pulmonar por Hantavirus (SPH) es una zoonosis grave transmitida por el roedor Calomys laucha, reservorio del virus hanta, que fue diagnosticado por primera vez en el chaco paraguayo en 1995. En el presente trabajo retrospectivo-descriptivo se
Insaurralde, Ariel; Instituto de Investigaciones en Ciencias de la Salud-UNA +1 more
core
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
[Diabetic neuropathy in patients with type 2 diabetes: the need for early diagnosis]. [PDF]
Aten PrimariaCampillo Piquer O, Lozano A.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Understanding how interculturality is taught and learned by students, professors, and academic authorities through phenomenography. [PDF]
Rev Esc Enferm USPAcuña CVP, Medina JL.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal +7 more
wiley +1 more source
[BVS Homeopatia Brasil: A historical review of its role in the visibility and access to homeopathic knowledge]. [PDF]
Rev Med Inst Mex Seguro SocRagacini LA, Chávez-Martínez O.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source