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La leishmaniosis es una enfermedad parasitaria con varias formas clínicas, desde lesiones cutáneas leves hasta enfermedades fatales con comprometimiento visceral. Existen varias técnicas moleculares como por ejemplo la reacción en cadena de la polimerasa
Lilian Chena +5 more
doaj
Moringa oleifera is a plant species well known for its high nutritional and functional value, whose seeds are a source of oil rich in Unsaturated Fatty Acids (UFAs), especially oleic acid.
Eva Coronel +6 more
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
PCR múltiple para la detección simultánea de los genes mecA y pvl en Staphylococcus spp
Este estudio observacional descriptivo de corte transverso tuvo por objetivo estandarizar una PCR múltiple para la detección simultánea de los genes mecA y pvl en Staphylococcus spp. Se emplearon como cepas control: S. aureus ATCC 25923, S.
María Leticia Carpinelli Acevedo +4 more
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Special World Day of tuberculosis. Stabilization of the global TB epidemic: WHO [PDF]
Uno de los objetivos del milenio se habría logrado diez años antes de la fecha meta. La enfermedad sigue matando cada día a cuatro mil cuatrocientas personas.
Instituto Nacional de Salud
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Detection of antibodies against Chlamydophila abortus in Costa Rican sheep flocks [PDF]
A total of 359 sheep samples from 15 flocks were analyzed for the presence of antibodies against Chlamydophila abortus using a commercial Enzyme linked Immunosorbent Assay (ELISA).
R. Villagra-Blanco +3 more
doaj
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Los cálculos renales se forman cuando la concentración de los componentes de la orina alcanzan un nivel en el cual es posible la cristalización.
R Guillén +4 more
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source

