Results 81 to 90 of about 573,262 (315)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

OBITUARIO - Prof. Dr. Martín Antonio Chiola Villagra 30 de Agosto de 1.938– 1º de Diciembre de 2.010

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2010
N ...
Alicia Schinin
doaj  

Current Situation and Perspectives on Hantaviruses in Mexico

Viruses, 2019
Hantaviruses are transmitted by rodents producing the hantavirus pulmonary syndrome (HPS) in the Americas. Today, no human cases of HPS have been reported in Mexico in spite of similar environmental conditions with Central America and the USA where ...
Ana L. Vigueras-Galván, Andrés M. López-Pérez, Gabriel E. García-Peña, Oscar Rico-Chávez, Rosa E. Sarmiento-Silva, Gerardo Suzán   +5 more
doaj   +1 more source

Experiencia de Sensibilización de Talento Humano en Salud en Atención Primaria en Salud (APS) por medio del Campus Virtual de Salud Pública (CVSP) Nodo Colombia (2013-15)

, 2017
 Objetivo: Ilustrar la experiencia de formación de Talento Humano en Salud (THS) en APS y RISS para Colombia por medio del Campus Virtual de Salud Pública (CVSP) de la OPS durante 2013 a 2015. Metodología: Se realizó una evaluación de procesos acadé
Henry Gutiérrez González; Profesor, Medicina, Universidad Libre de Cali, Rafael de Jesús Tuesca-Molina; Profesor, Departamento de Salud Pública, Universidad del Norte, Armando Guemes; Asesor de Sistemas y Servicios de Salud, Organización Panamericana de la Salud (OPS/OMS)., Erwin Hernando Hernández-Rincón; Centro de Estudios en Salud Comunitaria (CESCUS), de la Facultad de Medicina, de la Universidad de La Sabana, Colombia., Juan Eduardo Guerrero-Espinel; Facultad Nacional de Salud Pública, Universidad de Antioquia   +4 more
core  

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Investigación basada en el diseño para la promoción de Criticality: una propuesta Una Salud

Revista Eureka sobre Enseñanza y Divulgación de las Ciencias
La investigación basada en el diseño es una herramienta útil para formar al profesorado en el diseño, implementación y evaluación de situaciones de aprendizaje para el desarrollo de pensamiento crítico para la acción (criticality) en contextos socio ...
Irene González-Costa, Blanca Puig, Paloma Blanco-Anaya   +2 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

UJI Saludable: Una organización saludable y resiliente

, 2017
Introducción: El Proyecto Institucional UJI (Universitat Jaume I) Saludable se desarrolla desde el año 2012, con el objetivo de promocionar la salud y el bienestar de la comunidad universitaria, y de toda la sociedad sobre la base de la REUS y la Red Valenciana de Universidades Públicas Valencianas.
Salanova, M., Martínez, I.M., Ortega-Maldonado, A., Peláez, M.J., Ventura Campos, M., Corbu, E.A.   +5 more
openaire   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

A serum cytotoxicity assay for measuring the resistance of turbot to the ciliate Philasterides dicentrarchi

Comparative Immunology Reports
In previous studies we have found that the complement system plays an essential role in the resistance of fish to infection by the ciliate parasite Philasterides dicentrarchi.
Paola Guliás, Rosa Ana Sueiro, PhD, Oscar González, Cristina Brea, Joaquín Macías, José Manuel Leiro, PhD, Jesús Lamas, PhD   +6 more
doaj   +1 more source