Results 41 to 50 of about 340,590 (231)

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang   +12 more
wiley   +1 more source

Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors

open access: yesAdvanced Science, EarlyView.
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos   +6 more
wiley   +1 more source

Stress redistribution due to creep in nimonic 90 ministry of aviation contract no. PD/28/021 report for the period January 1964 - June 1965: part 1 [PDF]

open access: yes, 1965
The period covered by this report has been devoted to the design, construction development and calibration of a special apparatus to simulate the stress redistribution conditions occurring during the creep of a cooled turbine blade.
Clifton, T. E., Younger, A.
core  

On-Chip Transparent Wire Pipelining (invited paper) [PDF]

open access: yes, 2004
Wire pipelining has been proposed as a viable mean to break the discrepancy between decreasing gate delays and increasing wire delays in deep-submicron technologies.
Casu, Mario Roberto, Macchiarulo, Luca
core   +1 more source

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

open access: yesAdvanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu   +7 more
wiley   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen   +7 more
wiley   +1 more source

Full-Duplex Relaying in MIMO-OFDM Frequency-Selective Channels with Optimal Adaptive Filtering [PDF]

open access: yes, 2015
In-band full-duplex transmission allows a relay station to theoretically double its spectral efficiency by simultaneously receiving and transmitting in the same frequency band, when compared to the traditional half-duplex or out-of-band full-duplex ...
Lemos, João S.   +3 more
core   +2 more sources

Extending Battery Usage Time of a Heavy‐Duty Mecanum‐Wheeled Autonomous Electric Vehicle Used in Iron–Steel Industry by Considering Wheel Slippage

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
It is a fact that slippage causes tracking errors in both longitudinal and lateral directions which results to have less travel distance in tracking a reference trajectory. Less travel distance means having energy loss of the battery and carrying loads less than planned.
Gokhan Bayar   +2 more
wiley   +1 more source

Taking into account the influence of asymmetric traction load on the choice of the response parameters of blocking during oscillations of distance protection

open access: yesВестник Северо-Кавказского федерального университета
Introduction. The paper considers the problem of the influence of asymmetric traction load (ATL) on the functioning of relay protection, in particular, blocking during swings (BD) of distance protection (DP).Goal.
V. I. Nagay   +4 more
doaj   +1 more source

‘The System Can't Cope’: The Service System Response to Alcohol and Other Drug‐Facilitated Sexual Violence

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Alcohol and other drug‐facilitated sexual violence can have significant impacts on victim‐survivors, yet little is known about what support service providers offer them. To understand the experiences and perceptions of service providers, interviews with counsellors, health workers, forensic toxicologists and harm reduction workers were ...
Jessica Ison   +5 more
wiley   +1 more source

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