Results 81 to 90 of about 57,605 (331)

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

Voltage-Sensorless Control Scheme for a Grid Connected Inverter Using Disturbance Observer

Energies, 2017
A grid connected inverter usually requires voltage and current measurements to control the active and reactive powers as well as the inverter output currents.
Hyun-Sou Kim, Kyeong-Hwa Kim
doaj   +1 more source

Power quality and electromagnetic compatibility: special report, session 2 [PDF]

, 2015
The scope of Session 2 (S2) has been defined as follows by the Session Advisory Group and the Technical Committee: Power Quality (PQ), with the more general concept of electromagnetic compatibility (EMC) and with some related safety problems in ...
Desmet, Jan, Heimbach, Britta, Renner, Herwig   +2 more
core   +1 more source

Models, Methods and Network Topology: Experimental Design for the Study of Interference

, 2018
How should a network experiment be designed to achieve high statistical power? Ex- perimental treatments on networks may spread. Randomizing assignment of treatment to nodes enhances learning about the counterfactual causal effects of a social network ...
Bowers, Jake, Desmarais, Bruce A., Frederickson, Mark, Ichino, Nahomi, Lee, Hsuan-Wei, Wang, Simi   +5 more
core   +1 more source

Decoupled Double Synchronous Reference Frame current controller for unbalanced grid voltage conditions

2012 IEEE Energy Conversion Congress and Exposition (ECCE), 2012
Due to the growing changes in the electrical network related to the new distributed generation scheme and the integration of renewable energy sources, new requirements for grid-connected power converters are being defined in the new grid codes. The injection of positive- and negativesequence current components is becoming necessary for achieving new ...
Reyes, Manuel, Rodríguez Cortés, Pedro, Vazques, Sergio, Luna Alloza, Álvaro, Carrasco, Juan Manuel, Teodorescu, Remus   +5 more
openaire   +3 more sources

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Model predictive control of MMC-UPFC under unbalanced grid conditions

International Journal of Electrical Power & Energy Systems, 2020
Abstract This paper proposes a model predictive control (MPC) method to tackle the power flow control of the modular multilevel converter based unified power flow controller (MMC-UPFC) under unbalanced grid conditions. The predictive models corresponding to the discrete-time models of MMC-UPFC are derived.
Qiufan Yang, Ting Ding, Hengxin He, Xia Chen, Fengbo Tao, Zhicheng Zhou, Yang Xu, Shu Chen   +7 more
openaire   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Research of control strategy for VSC-HVDC system under unbalanced grid voltage conditio

Gong-kuang zidonghua, 2013
In view of problems of harmonic and power fluctuation of DC and AC side of VSC-HVDC system under unbalanced grid voltage condition, the paper used dual dq-PI control strategy with respective direction of positive and negative sequence components of grid ...
SUN Bo, ZHANG Jian-wen, PAN Lei-luo, HAN Gang   +3 more
doaj   +1 more source