Results 31 to 40 of about 742,712 (288)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
MathematicsThis paper investigates a class of third-order partial differential equations with an unbounded lower-order coefficient in the Hilbert space L2(R2). The study is motivated by the wide use of third-order equations, particularly of Korteweg–de Vries type ...
Sabit Igissinov +4 more
doaj +1 more source
Drag on a slip spherical particle moving in a couple stress fluid
Alexandria Engineering Journal, 2016 The creeping motion of a rigid slip sphere in an unbounded couple stress fluid is investigated. The linear slip boundary condition and the vanishing couple stress condition are applied on the surface of the sphere.
E.A. Ashmawy
doaj +1 more source
Fourth-order operators with unbounded coefficients
Communications on Pure and Applied AnalysisWe prove that operators of the form $A=-a(x)^2Δ^{2}$, with $|D a(x)|\leq c a(x)^\frac{1}{2}$, generate analytic semigroups in $L^p(\mathbb{R}^N)$ for ...
Gregorio F., Spina C., Tacelli C.
openaire +2 more sources
Backward stochastic differential equations with unbounded coefficients and their applications [PDF]
In this thesis, we focus on problems on the theory of Backward Stochastic Differential Equations (BSDEs). In particular, BSDEs with an unbounded generator are considered, under various conditions (on the generator).
Li, Jiajie
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Қарағанды университетінің хабаршысы. Математика сериясы, 2021 The article deals with the existence of a generalized solution for the second order nonlinear differential equation in an unbounded domain. Intermediate and lower coefficients of the equation depends on the required function and considered smooth.
A.N. Yesbayev, M.N. Ospanov
doaj +1 more source
Quantum stochastic differential equations and continuous measurements: unbounded coefficients
, 2011 A natural formulation of the theory of quantum measurements in continuous time is based on quantum stochastic differential equations (Hudson-Parthasarathy equations).
BARCHIELLI, ALBERTO +3 more
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Estimates for the transition kernel for elliptic operators with unbounded coefficients [PDF]
, 2023 2021 - 2022This manuscript is devoted to the study of the qualitative behaviour of the solutions of evolution equations arising from elliptic and parabolic problems on unbounded domains with unbounded coefficients.
Porfido, Marianna
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source