Results 141 to 150 of about 11,243 (308)

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

On Chlodowsky Variant of (p,q) Kantorovich-Stancu-Schurer Operators

International Journal of Analysis and Applications, 2016
In the present paper, we introduce the Chlodowsky variant of (p,q) Kantorovich-Stancu-Schurer operators on the unbounded domain which is a generalization of (p,q) Bernstein-Stancu-Kantorovich operators.
Vishnu Narayan Mishra, Shikha Pandey
doaj   +2 more sources

Approximation by Entire Functions on Unbounded Domains in

Journal of Approximation Theory, 1993
AbstractGiven a function analytic in an unbounded domain of Cn with certain estimates of growth, we construct an entire function approximating it with a certain rate in some inner domain and give estimates of growth of the approximating function. This extends well-known results of M. V. Keldysh to several variables and more general domains.
openaire   +1 more source

Genetic Programming for the Evolution of Functions with a Discrete Unbounded Domain

, 2013
The idea of automatic programming using the genetic programming paradigm is a concept that has been explored in the work of Koza and several works since.
Eastwood, Shawn
core  

Learning unbounded-domain spatiotemporal differential equations using adaptive spectral methods

Rapidly developing machine learning methods have stimulated research interest in computationally reconstructing differential equations (DEs) from observational data, providing insight into the underlying mechanistic models.
Li, Xiangting, Chou, Tom, Shen, Qijing, Xia, Mingtao   +3 more
core   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

Stochastic diffusion on an unbounded domain [PDF]

Pacific Journal of Mathematics, 1979
openaire   +3 more sources

CHERNOFF-LIKE COUNTEREXAMPLES RELATED TO UNBOUNDED OPERATORS

In this paper, we give an example of a closed unbounded operator whose square domain and adjoint's square domain are equal and trivial.
Mohammed Hichem Mortad, Souheyb Dehimi
core   +1 more source