Results 221 to 230 of about 85,222 (279)

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

Vortex equilibria using least-squares methods. [PDF]

open access: yesTheor Comput Fluid Dyn
Harris SJ, McDonald NR.
europepmc   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

open access: yesAdvanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim   +7 more
wiley   +1 more source

Plume-scale confinement on thermal convection. [PDF]

open access: yesProc Natl Acad Sci U S A
Noto D, Letelier JA, Ulloa HN.
europepmc   +1 more source

All-optical permittivity-asymmetric quasi-bound states in the continuum. [PDF]

open access: yesLight Sci Appl
Berté R   +4 more
europepmc   +1 more source

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