Results 41 to 50 of about 184,610 (206)

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Biogeography-Based Combinatorial Strategy for Efficient AUV Motion Planning and Task-Time Management

, 2016
Autonomous Underwater Vehicles (AUVs) are capable of spending long periods of time for carrying out various underwater missions and marine tasks. In this paper, a novel conflict-free motion planning framework is introduced to enhance underwater vehicle's
Powers, David MW, Sammut, Karl, Yazdani, Amirmehdi, Zadeh, Somaiyeh Mahmoud   +3 more
core   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Consumer phase identification in distribution grids using Graph Neural Networks based on synthetic and measured power profiles

Energy and AI
Most distribution system operators may not accurately record or completely maintain the phase connections for the numerous LV customers. Different consumer phase identification (CPI) approaches based on voltages, powers or other measurements are proposed
Chandra Sekhar Charan Dande, Nikolaos A. Efkarpidis, Matthias Christen, Mirko Ginocchi, Antonello Monti   +4 more
doaj   +1 more source

From Pixels to Buildings: End-to-end Probabilistic Deep Networks for Large-scale Semantic Mapping

, 2019
We introduce TopoNets, end-to-end probabilistic deep networks for modeling semantic maps with structure reflecting the topology of large-scale environments. TopoNets build a unified deep network spanning multiple levels of abstraction and spatial scales,
Pronobis, Andrzej, Zheng, Kaiyu
core   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Impact of Geopolitical and International Trade Dynamics on Corporate Vulnerability and Insolvency Risk: A Graph-Based Approach

Information
In the context of the globalization process, the interplay between geopolitical dynamics and international trade fluctuations has had significant effects on global economic and business stability.
Yu Zhang, Elena Sánchez Arnau, Enrique A. Sánchez Pérez   +2 more
doaj   +1 more source

A Hierarchal Planning Framework for AUV Mission Management in a Spatio-Temporal Varying Ocean

, 2017
The purpose of this paper is to provide a hierarchical dynamic mission planning framework for a single autonomous underwater vehicle (AUV) to accomplish task-assign process in a limited time interval while operating in an uncertain undersea environment ...
Atyabi, Adham, Powers, David M. W, Sammut, Karl, Yazdani, Amir Mehdi, Zadeh, Somaiyeh Mahmoud.   +4 more
core   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

Querying Probabilistic Neighborhoods in Spatial Data Sets Efficiently

, 2016
$\newcommand{\dist}{\operatorname{dist}}$ In this paper we define the notion of a probabilistic neighborhood in spatial data: Let a set $P$ of $n$ points in $\mathbb{R}^d$, a query point $q \in \mathbb{R}^d$, a distance metric $\dist$, and a ...
D Krioukov, H Samet, H-P Kriegel, HW Hethcote, L Arge, M Looz von, R Aldecoa, V Batagelj   +7 more
core   +1 more source