Results 71 to 80 of about 662,561 (296)

Improved analyses of changes and uncertainties in sea surface temperature measured in situ sice the mid-nineteenth century: The HadSST2 dataset [PDF]

open access: yes, 2006
A new flexible gridded dataset of sea surface temperature (SST) since 1850 is presented and its uncertainties are quantified. This analysis [the Second Hadley Centre Sea Surface Temperature dataset (HadSST2)] is based on data contained within the ...
Folland, C. K.   +7 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Ecological City of Bojnourd Based on Scenario-based Future Studies [PDF]

open access: yesبرنامه‌ریزی توسعه شهری و منطقه‌ای, 2019
The ecological city approach is one emerging of area, which has provided different perspectives on cities in terms of environmental and social dimensions.
Mahmoud Jomehpour   +2 more
doaj   +1 more source

COMPONENTS OF UNCERTAINTY

open access: yesInternational Economic Review, 2017
AbstractUncertainty is acknowledged to be a source of economic fluctuations. But, does the type of uncertainty matter for the economy's response to an uncertainty shock? This article offers a novel identification strategy to disentangle different types of uncertainty.
openaire   +6 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Seismic codes based equivalent nonlinear and stochastic soil structure interaction analysis

open access: yesStudia Geotechnica et Mechanica, 2020
The aim of this study is to consider the effects of the variation of shear modulus ratio (G/G0) and damping ratio (ξ) of soil, obtained by a linear iterative method based on the design spectra of seismic codes, the soil environment in terms of ...
Guellil Mohamed Elhebib   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Adaptive and Robust Fault-Tolerant Tracking Control of Contact force of Pantograph-Catenary for High-Speed Trains [PDF]

open access: yes, 2015
This paper presents a modified multi-body dynamic model and a linear time-invariant model with actuator faults (loss of effectiveness faults, bias faults) and matched and unmatched uncertainties.
Yan, Xinggang   +3 more
core   +1 more source

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